Results 201 to 210 of about 5,988,827 (313)

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Nine changes needed to deliver a radical transformation in biodiversity measurement. [PDF]

Proc Natl Acad Sci U S A
Sutherland WJ, Burgess ND, Edwards SV, Jones JPG, Soltis PS, Tilman D, Allen JM, Andrianandrasana HT, Armour CJ, August T, Bawa KS, Bailey S, Birch T, Boersch-Supan PH, Cavender-Bares J, Blaxter M, Chaplin-Kramer R, Daru BH, De Palma A, Eisenberg C, Elphick CS, Freckleton RP, Frick WF, Gonzalez A, Goetz SJ, Greenspoon L, Grozingeree CM, Hankins DL, Hazell J, Isaac NJB, Lambertini M, Lewin HA, Mac Aodha O, Madhavapeddy A, Milner-Gulland EJ, Milo R, O'Dwyer J, Purvis A, Salafsky N, Tallis H, Tanshi I, Vijay V, Wikelski M, Williams DR, Woodard SH, Robinson GE.   +45 more
europepmc   +1 more source

The Shrinking World: Ecological Consequences of Habitat Loss [PDF]

BioScience, 2006
openaire   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

Advanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du   +12 more
wiley   +1 more source

Cutaneous leishmaniasis: emerging insights in epidemiology, diagnosis, and treatment. [PDF]

Front Pharmacol
Kumar N, Kakru DK, Arcot R, Lakhanpal S, Singh SK, Kumar S, Reneus Paul J.   +6 more
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Clarifying space use concepts in ecology: Range vs. occurrence distributions. [PDF]

Ecology
Alston JM, Fleming CH, Noonan MJ, Tucker MA, Silva I, Folta C, Akre TSB, Ali AH, Belant JL, Beyer D, Blaum N, Böhning-Gaese K, de Paula RC, Dekker J, Drescher-Lehman J, Farwig N, Fichtel C, Fischer C, Ford AT, Janssen R, Jeltsch F, Kappeler PM, LaPoint SD, Markham AC, Medici EP, Morato RG, Nathan R, Olson KA, Patterson BD, Petroelje TR, Ramalho EE, Rösner S, Oliveira-Santos LGR, Schabo DG, Selva N, Sergiel A, Spiegel O, Ullmann W, Zięba F, Zwijacz-Kozica T, Wittemyer G, Fagan WF, Müller T, Calabrese JM.   +43 more
europepmc   +1 more source

Multi‐Scale Mapping of Gene Expression from Whole‐slide Images for Identifying Phenotype‐Associated Subpopulations

Advanced Science, EarlyView.
BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng, Jiajing Xie, Luqi Wang, Hailong Xie, Tong Zhi, Yujia Guo, Bofeng Zhu, Dong Wang, Yu Chen   +8 more
wiley   +1 more source

Behavioural ecology in the twenty-first century. [PDF]

Nat Ecol Evol
West SA, Dall SRX, Cunningham JP, Alonzo SH, Griffin AS.   +4 more
europepmc   +1 more source