Results 131 to 140 of about 18,044,417 (315)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The perceived beauty of art is not strongly calibrated to the statistical regularities of real-world scenes

Scientific Reports
Aesthetic judgements are partly predicted by image statistics, although the extent to which they are calibrated to the statistics of real-world scenes and the ‘visual diet’ of daily life is unclear.
Alexander Swartz, Alice E. Skelton, George Mather, Jenny M. Bosten, John Maule, Anna Franklin   +5 more
doaj   +1 more source

Worldview Semantic Stratum in Volunteers with Intrinsic and Extrinsic Motivations

СибСкрипт
Volunteering holds great social significance. As more people get involved, social volunteering becomes increasingly diverse. The study explores the semantic stratum in the image of the world and the lifestyle of volunteers with different extrinsic and ...
Vitaliy V. Kalita, Yana I. Flakh
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Reputation and Image from the Perspective of Management Sociology

Дискурс
Introduction. The digital world is reshaping established realities by enabling social entities to manifest in the online world. Within this evolving framework, reputation increasingly detaches from the individual being assessed, influencing both the ...
M. V. Shutova
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Multi-task learning with self-learning weight for image denoising

Journal of Engineering and Applied Science
Background Image denoising technology removes noise from the corrupted image by utilizing different features between image and noise. Convolutional neural network (CNN)-based algorithms have been the concern of the recent progress on diverse image ...
Qian Xiang, Yong Tang, Xiangyang Zhou
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

THE IMPACT OF LINGUISTIC CONSCIOUSNESS ON THE WORLD IMAGE

, 2020
This article highlights the investigation of the world image, which is one of the fields of cognitive linguistics, which involves the concept of cognitive problems and their reflection in language, as a set of objective expressions that reflect the concentration of experience of a particular language community in language as a transmitter of certain ...
openaire   +2 more sources