Results 91 to 100 of about 17,095,133 (303)
Small-World Networks in Geophysics
, 2010 Many geophysical processes can be modelled by using interconnected networks. The small-world network model has recently attracted much attention in physics and applied sciences.
Barthelemy +13 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Current Status of the Integrated Circuit Industry in China ― IC Manufacturing Industry
Journal of Microelectronic Manufacturing, 2019 Litho World
doaj +1 more source
GeosciencesAsbestos, consisting of six natural mineral fibrous silicate phases, was widely utilized in industrial development during the 20th century and has left a global legacy of health, environmental, and regulatory challenges.
Alessandro Croce +6 more
doaj +1 more source
Information Access in a Multilingual World: Transitioning from Research to Real-World Applications [PDF]
, 2009 Multilingual Information Access (MLIA) is at a turning point wherein substantial real-world applications are being introduced after fifteen years of research into cross-language information retrieval, question answering, statistical machine translation ...
Gey, Fredric +2 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Global progress on the elimination of viral hepatitis as a major public health threat: an analysis of WHO Member State responses 2017 [PDF]
, 2019 Blach +22 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source