Results 31 to 40 of about 119,866 (260)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...Dylan Casey, Zeqian Gao, Joan Boyeswiley +1 more sourceWhat About Susan? Gender in Narnia [PDF]
, 2017 Critics of C.S. Lewis argue that his misogyny is present in his portrayal of female characters. While Lewis himself was self-contradictory in his attitudes towards women, his depictions of female characters in The Chronicles of Narnia are both realistic ...Schilling, Emma G.core +1 more sourceIn situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen +11 morewiley +1 more sourceSequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang +10 morewiley +1 more sourceCell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten +5 morewiley +1 more sourceInhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski +7 morewiley +1 more sourceWriting in Britain and Ireland, c. 400 to c. 800 [PDF]
, 2012 No abstract ...Abrams, Abrams, Adams, Adomnán, Adomnán, Adomnán, Agamben, Ahlqvist, Alcock, Alcuin, Alcuin, Aldhelm, Aldhelm, Aldhelm, Aldhelm, Allen, Amodio, Amundsen, Anderson, Anderson, Andersson, Andrews, Anlezark, Anlezark, Arbuthnot, Armstrong, Asser, Asser, Assmann, Atkinson, Attenborough, Augustine, Ayoub, Aðalbjarnarson, Baader, Baker, Baker, Baker, Bannerman, Bannerman, Barker, Barlow, Barlow, Barlow, Barlow, Barlow, Barnes, Barnes, Barthes, Bartlett, Bartlett, Bartlett, Baswell, Bately, Bately, Bately, Bately, Bately, Bately, Bately, Bates, Baxter, Bayless, Beccaria, Beck, Becker, Bede, Bede, Bede, Bede, Bede, Bede, Bede, Bede, Bede, Bede, Bede, Benedeit, Benjamin, Benson, Bernard, Best, Best, Bestul, Bethurum, Bhreathnach, Bhreathnach, Bhreathnach, Bieler, Bierbaumer, Binchy, Binchy, Binchy, Binski, Bisagni, Bischoff, Bischoff, Bischoff, Bischoff, Bischoff, Bishop, Bishop, Bishop, Bishop, Bishop, Bishop, Bishop, Bjork, Bjork, Black, Black, Blair, Blair, Blake, Blake, Blanton, Bliss, Bloomfield, Blunt, Bober, Boenig, Boll, Bolton, Boniface, Boniface, Boniface, Boniface, Bonner, Bonner, Bonser, Borst, Borst, Borst, Boryslawski, Bosworth, Boyle, Boym, Boynton, Bracken, Bradbury, Bradley, Brady, Breatnach, Breatnach, Breatnach, Breatnach, Bredehoft, Bredehoft, Bremmer, Broecker, Bromwich, Bromwich, Brooks, Brooks, Brooks, Brooks, Brooks, Broun, Broun, Brown, Brown, Brown, Brown, Brown, Brown, Bruce-Mitford, Bruckner, Budny, Bullough, Bullough, Buttimer, Bynum, Byrne, Cabrol, Cain, Calder, Cameron, Cameron, Cameron, Cameron, Campbell, Campbell, Campbell, Campbell, Campbell, Campbell, Campbell, Campbell, Campbell, Candon, Cannon, Carabine, Careri, Carey, Carey, Carey, Carey, Carey, Carey, Carey, Carey, Carey, Carey, Carney, Carney, Carney, Carney, Carney, Carnicelli, Carroll, Cavill, Cavill, Cavill, Certeau, Certeau, Chadwick, Chambers, Chaplais, Chaplais, Charles-Edwards, Charles-Edwards, Charles-Edwards, Charles-Edwards, Charles-Edwards, Chickering, Chickering, Clackson, Clancy, Clancy, Clancy, Clancy, Clancy, Clancy, Clancy, Clancy, Clancy, Clancy, Clancy, Clark, Clark, Clarke, Clemoes, Clemoes, Clemoes, Coates, Cockayne, Cohen, Colgrave, Colgrave, Colgrave, Colgrave, Colgrave, Colker, Colker, Columbanus, Conner, Connon, Conte, Cooper, Cooper, Cordoliani, Cordoliani, Corthals, Crawford, Crick, Crick, Crick, Crombie, Cronan, Cross, Cubbin, Curran, Da Rold, Damico, Dance, Darlington, Davies, Davies, Davies, Davies, Davies, Davies, Davies, Davis, Davis, Davis, Davis, de Vriend, de Vries, Dean, Deegan, DeGregorio, Dekker, Derolez, Derrida, Dickins, Discenza, Discenza, Discenza, Discenza, Doane, Doane, Dobbie, Dobbie, Dobbs, Doherty, Doherty, Donaldson, Donoghue, Donoghue, Dooley, Doubleday, Downey, Downham, Downham, Dronke, Dronke, Drögereit, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dumville, Dunning, Dümmler, Dümmler, D’Aronco, D’Aronco, D’Aronco, Eadmer, Earl, Eastwood, Edson, Egilsson, Eichorn-Mulligan, Einarsson, Eisenhofer, Evans, Evans, Evans, Ewald, Farmer, Farrell, Fehr, Fehr, Fell, Fell, Fell, Fellows-Jensen, Fidjestøl, Fidjestøl, Fidjestøl, Fidjestøl, Finke, Fischer, Fleming, Flower, Flynn, Foot, Foot, Ford, Forsyth, Forsyth, Forsyth, Forsyth, Fowler, Fox, Frank, Frank, Frankis, Franklin, Frantzen, Frantzen, Frantzen, Frantzen, Fraser, Frere, Frese, Friedman, Frithegod, Fry, Fulk, Fulk, Fulk, Fulk, Fulk, Fulton, Fulton, Förster, Gaimar, Galbraith, Gameson, Gameson, Gameson, Gameson, Gameson, Gameson, Ganz, Ganz, Ganz, Garmonsway, Garrison, Garrison, Geddes, Gelling, Gelting, Georgianna, Germann, Gerritsen, Gibson, Gilbert, Gildas, Gittos, Glorie, Gneuss, Gneuss, Gneuss, Gneuss, Gneuss, Godden, Godden, Godden, Godden, Godden, Godden, Godden, Godden, Godman, Godman, Goffart, Goffart, Goldberg, Gonser, Goolden, Gorman, Gottschaller, Graham, Graham-Campbell, Grammaticus, Gransden, Grant, Grattan, Gray, Gray, Gray, Gray, Green, Green, Green, Green, Greene, Greene, Greene, Greenfield, Greenway, Gretsch, Gretsch, Gretsch, Gretsch, Griffith, Griffith, Griffiths, Griffiths, Grossi, Gruffydd, Guðnason, Gwara, Gwara, Gwynn, Günzel, Hadley, Hall, Halldórsson, Halldórsson, Handley, Hanning, Hansen, Hanslik, Hare, Harmer, Harper, Harris, Harris, Harris, Harris, Harrison, Harrison, Hart, Hart, Harvey, Harvey, Harvey, Harvey, Haycock, Haycock, Hayward, Head, Head, Heaney, Hecht, Hemming, Henel, Hennessy, Henry, Henry, Henry, Herbert, Herbert, Herbert, Herbert, Herbert, Herren, Herren, Hervey, Heslop, Heyworth, Higgitt, Higham, Hildebert, Hill, Hill, Hill, Hill, Hines, Hines, Hines, Hinton, Hinton, Hofmann, Hofmann, Hofstetter, Holcomb, Holder-Egger, Hollis, Hollis, Hollis, Hollis, Hollis, Holsinger, Hooke, Horner, Hough, Houghton, Howald, Howard-Johnston, Howe, Howe, Howe, Howe, Howe, Howe, Howlett, Hughes, Hughes, Hughes, Hughes, Hughes, Hughes, Hull, Hull, Huneycutt, Huneycutt, Hunt, Hunter, Huws, Ingram, Ireland, Irvine, Irvine, Irvine, Irvine, Irving, Irving, Isaac, Isaac, Isaac, Isaac, Jackson, Jackson, Jackson, Jacquart, James, James, Jankulak, Jarman, Jarman, Jayatilaka, Jenkins, Jenkins, Jenkinson, Jesch, Jesch, John, Johnson, Jolly, Jones, Jones, Jones, Jones, Joy, Joynt, Jónsson, Jónsson, Karkov, Karkov, Karkov, Karkov, Karkov, Karkov, Kaufmann, Keefe, Keefer, Keefer, Keefer, Keefer, Keil, Kelleher, Kellogg, Kelly, Kelly, Kelly, Kelly, Kelly, Kelly, Kenney, Ker, Ker, Kershaw, Keynes, Keynes, Keynes, Keynes, Keynes, Keynes, Keynes, Keynes, Keynes, Keynes, Keynes, Kim, King, Klaeber, Klein, Kleinschmidt, Kleinschmidt, Klinck, Klinck, Klinck, Knight, Knott, Koch, Korhammer, Kotzor, Krapp, Krapp, Krapp, Krapp, Krause, Kristeller, Kuhn, Kuhn, Kurath, Kuypers, LaCapra, Lambert, Lambkin, Langefeld, Langmuir, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Lapidge, Latour, Law, Law, Lawson, Laynesmith, Leake, Leclercq, Leclercq, Lees, Lees, Lees, Lees, Lees, Legge, Lehmann, Lerer, Lerer, Leslie, Leslie, Letson, Levison, Liebermann, Lindsay, Lindsay, Liuzza, Liuzza, Liuzza, Liuzza, Liuzza, Liuzza, Liuzza, Liuzza, Lockett, Lockett, Lord, Love, Love, Lowe, Lowe, Lowe, Lowe, Lowe, Loyn, Loyn, Lucas, Lund, Lutz, Löweneck, Mac Airt, Mac Airt, Mac Cana, Mac Cana, Mac Cana, Mac Eoin, Mac Mathúna, Mac Niocaill, Macalister, MacBain, Mack, Mack, MacQueen, Macrae-Gibson, Magennis, Magoun, Mall, Mallory, Mallory, Malmer, Mantello, Marsden, Martin, Mason, Mason, Massey, Matthew, Mattingly, Matzner, McCarthy, McCluskey, McCone, McCone, McCone, McGurk, McGurk, McKee, McKenna, McKitterick, McLeod, McManus, McManus, McNamara, McNamara, Meaney, Meritt, Meyer, Meyer, Meyer, Michelet, Miles, Miller, Mills, Mitchell, Moeller, Moisl, Momma, Momma, Mora, Morini, Morton, Muir, Munske, Murdoch, Murdoch, Murphy, Murphy, Murphy, Murphy, Murray, Mynors, Márkus, Nash-Williams, Nelson, Nennius, Neuman de Vegvar, Neville, Nielsen, Niles, Nordal, Nordal, North, Nutton, Ní Bhrolcháin, Ní Mhaonaigh, Ní Mhaonaigh, Ní Mhaonaigh, Ní Mhaonaigh, NíMhaonaigh, NíMhaonaigh, Oliver, Ommundsen, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Orchard, Ortenberg, Orton, Osborn, Oswald, Otter, Overing, Overing, Owen, Owen, O’Brien O’Keeffe, O’Brien O’Keeffe, O’Brien O’Keeffe, O’Brien O’Keeffe, O’Connor, O’Donnell, O’Keeffe, O’Neill, O’Neill, O’Neill, O’Rahilly, O’Rahilly, O’Reilly, Padel, Padel, Page, Page, Palazzo, Parkes, Parkes, Parkes, Parkes, Parkes, Parsons, Parsons, Parsons, Parsons, Pasternack, Patrick, Perello, Pettit, Pfaff, Pfaff, Pfaff, Pheifer, Plummer, Pons-Sanz, Poole, Poole, Poole, Poole, Pope, Pope, Poppe, Porter, Pratt, Pratt, Preminger, Prescott, Prescott, Press, Pryce, Quinn, Radner, Ramsay, Ranger, Rauer, Raw, Raw, Redknap, Reuter, Rhodes, Richards, Ridyard, Ridyard, Riedinger, Rigg, Rigg, Roberts, Roberts, Roberts, Roberts, Roberts, Robertson, Robinson, Robinson, Robinson, Robinson, Rodway, Rodway, Roest Crollius, Rollason, Rollason, Rollason, Rollason, Rollason, Rollason, Rollason, Rollason, Ross, Rowland, Rowland, Rowland, Rowley, Rubin, Rudolf, Rumble, Russom, Russom, Rypins, Sahlins, Sahlins, Said, Sauer, Sauer, Sauer, Sawyer, Sawyer, Scharer, Schauman, Schipperges, Schlüter, Schmeidler, Schröer, Schwab, Schöner, Scott, Scott, Scragg, Scragg, Scragg, Scragg, Scragg, Scragg, Selmer, Semper, Shanzer, Sharpe, Sharpe, Shields, Shippey, Shippey, Shippey, Short, Short, Short, Siegel, Sievers, Sievers, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Sims-Williams, Singer, Sisam, Sisam, Skeat, Smalley, Smith, Smith, Smith, Smith, Smithers, Smyth, Southern, Spiegel, St-Jacques, Stafford, Stanley, Stanley, Stanley, Stanton, Steiner, Stenton, Stenton, Stephenson, Stephenson, Stevens, Stevenson, Stevenson, Stevenson, Stock, Stokes, Stokes, Stokes, Stokes, Stokes, Stokes, Stokes, Stokes, Stokes, Stokes, Stokes, Stork, Strecker, Strohm, Stubbs, Studer, Summerson, Sveinsson, Swan, Swanton, Sweet, Sweet, Symons, Szarmach, Szarmach, Szarmach, Szarmach, Tachiaos, Talbot, Talbot, Talbot, Tatwine, Taylor, Tedeschi, Tedeschi, Temkin, Temkin, Terasawa, Thacker, Thacker, Thier, Thomas, Thompson, Thompson, Thomson, Thornbury, Thornbury, Thorpe, Thundy, Thurneysen, Thurneysen, Tilliette, Tilliette, Timmer, Tinti, Todd, Toner, Toner, Toner, Toswell, Townend, Townend, Townend, Townend, Treharne, Treharne, Treharne, Treharne, Treharne, Treharne, Trilling, Tristram, Tristram, Tschan, Tupper, Turner, Turner, Turner, Tyler, Tyler, Tyler, Tyler, Tyler, Tymoczko, Tymoczko, Ure, Urquhart, van Arsdall, Van de Vyver, van der Horst, van Els, van Hamel, van Houts, van Houts, van Houts, Vanderbilt, Vendler, von See, Vössen, Walberg, Wallace-Hadrill, Wallis, Wallis, Walsh, Walther, Ward, Ward, Ward, Warren, Watt, Webb, Webster, Webster, Webster, Webster, Wehlau, Wenisch, Weston, Whalen, Whatley, White, Whitelock, Whitelock, Whitelock, Whitelock, Whitelock, Whitelock, Whitelock, Whitelock, Whitelock, Whitelock, Wickersheimer, Wieland, Wilcox, Wiley, Williams, Williams, Williams, Williamson, Williamson, Wilmart, Wilson, Winterbottom, Winterbottom, Winterbottom, Winterbottom, Winterbottom, Wiseman, Wogan-Browne, Wogan-Browne, Wogan-Browne, Wolf, Wolfram, Wollmann, Wood, Woolf, Woolf, Woolf, Woolf, Wormald, Wormald, Wormald, Wormald, Wormald, Wormald, Wormald, Wormald, Wormald, Wormald, Wormald, Wrenn, Wright, Wright, Wright, Yorke, Yu, Zink, Ziolkowski, Zupitza, Æthelweard, Æthelwulf, Ó Cróinín, Ó Cróinín, Ó hAodha, Ó hUiginn, Ó Néill, Ó Néill, Ó Riain, Ó Riain, Ó Carragáin, Ó Carragáin, Ó Cathasaigh, Ó Cathasaigh, Ó Cathasaigh, Ó Cathasaigh, Ó Cathasaigh, Ó Cathasaigh, Ó Concheanainn, Ó Concheanainn, Ó Corráin, Ó Corráin, Ó hAodha +1241 morecore +1 more source
