Results 61 to 70 of about 119,866 (260)

\u3cem\u3eThe Chronicles of Narnia\u3c/em\u3e, and How C.S. Lewis Created Christian Fantasy Fiction [PDF]

open access: yes, 2015
C.S. Lewis was a pioneer in combining the ideas of fantasy and Christian literature, before the fantasy genre alone was even acknowledged. Christian fantasy fiction, as a fiction sub-genre, can be identified as a piece of fiction with fantastical ...
Callow, Amanda
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Chronicling menstrual cycle patterns across the reproductive lifespan with real world data

open access: yesScientific Reports
AbstractBackgroundThe intricate hormonal and physiological changes of the menstrual cycle can influence health on a daily basis. Although prior studies have helped improve our understanding of the menstrual cycle, they often lack diversity in populations included, sample size, and the span of reproductive and life stages.
Adam C. Cunningham   +6 more
openaire   +3 more sources

Inward, Outward, Onward: Autoethnography of a Dissertation in (Qualitative) Transitional Space [PDF]

open access: yes, 2011
This article presents the connection of a personal dissertation process to the wider world of qualitative research. Using the concept of transitional space as a metaphor, the author chronicles her theoretical transition from critical race theory to ...
Harris, Genevieve
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Rotulus: Chronicle of the History of the World

open access: yesArchivalia
https://www.library.upenn.edu/exhibits/chronicle ...
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Persuasive discourse and language planning in Ireland [PDF]

open access: yes, 2011
Colonial language discourse typically consists of evaluations concerning the respective merits of two or more languages, and the cultures they represent. This can serve as a warrant for imposing a ‘superior’ language.
Gray G, Mazzon G
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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