Results 41 to 50 of about 3,421,670 (302)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Problems and Prospects of the Russian Financial Market in the Context of Structural Changes in the World Economy

open access: yesФинансы: теория и практика, 2020
The article is based on the author’s report “On the root causes of the growing chaos and measures to overcome the economic crisis”. The aim of the article is to analyze the problems of the modern financial market system in the world and in Russia and to ...
S. Yu. Glaz’ev
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Speculative Attacks or Economic Fundamentals: Evidence from the Asian Currency Crisis [PDF]

open access: yes, 2000
This paper argues that what led to the Asian financial crisis was a fatal combination of several self-reinforcing factors including external sector weaknesses, fragility in domestic financial markets due to inadequately administered financial ...
Chowdhury, Abdur
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

ECONOMIC SECURITY IN THE SYSTEM OF TRANSFORMATION OF THE WORLD FINANCIAL ARCHITECTURE

open access: yesСтратегические решения и риск-менеджмент, 2010
Transformation of world financial architecture (WFA) is offered to be carried out with use of model of the geostrategy formed within the limits of a triad of institutes «geopolitics-geoeconomy-geonomika».
V. P. Bauer, V. I. Avdiyskiy
doaj   +1 more source

Real estate investment in global financial centers: risk, return and contagion [PDF]

open access: yes, 2009
Global financial activity is heavily concentrated in a small number of world cities –international financial centers. The office markets in those cities receive significant flows of investment capital.
Lizieri, C.
core  

Contagious Synchronization and Endogenous Network Formation in Financial Networks [PDF]

open access: yes, 2014
When banks choose similar investment strategies the financial system becomes vulnerable to common shocks. We model a simple financial system in which banks decide about their investment strategy based on a private belief about the state of the world and ...
Aymanns, Christoph, Georg, Co-Pierre
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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