A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Global distribution and health impact of infectious disease outbreaks, 1996-2023: a worldwide retrospective analysis of World Health Organization emergency event reports. [PDF]
Liu Q+6 more
europepmc +1 more source
Similar 9-year mortality risks and reproducibility for the World Health Organization and American Diabetes Association glucose tolerance categories: the Hoorn Study. [PDF]
Femmie de Vegt+5 more
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AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng+7 more
wiley +1 more source
Cardiovascular risk profile in individuals with borderline glycemia: the effect of the 1997 American Diabetes Association diagnostic criteria and the 1998 World Health Organization Provisional Report. [PDF]
Sungmook Lim+4 more
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Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani+2 more
wiley +1 more source
Validation of the World Health Organization Rehabilitation Competency Framework: An illustration using physiotherapy. [PDF]
Mocke M, Unger M, Hanekom S.
europepmc +1 more source
Dreamscapes of World Health: The History of the World Health Organization
openaire +2 more sources
Clustering of lifetime substance use and sexual intercourse among young people: analysis of two school-based surveys [PDF]
Bartlett R.+8 more
core +1 more source
Thyroid volumes in a national sample of iodine-sufficient swiss school children: comparison with the World Health Organization/International Council for the control of iodine deficiency disorders normative thyroid volume criteria [PDF]
Sonja Y. Hess, MB Zimmermann
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