Results 131 to 140 of about 5,929,395 (302)
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Canada and the First World War: A Canadian War Museum Internet Exhibition [PDF]
Canada and the First World War is the largest internet resource ever developed by the Canadian War Museum. The goal of this site is to provide visitors across the country and around the world with the most comprehensive and authoritative site for the ...
Cook, Tim, Lyons, Kathryn
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
”I Speak Hip Hop”: An Informative Interview about Generation Hip Hop and the Universal Hip Hop Museum [PDF]
”I Speak Hip Hop” is an interview of members of Generation Hip Hop and the Universal Hip Hop Museum. This primary source highlights two Hip Hop organizations with chapters around the world.
Harris, Travis T., Iglesias, Tasha
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Civil War Conclusions: What PBS\u27 Freedom Riders Can Teach Us [PDF]
We often have a deep problem in the Historical community. We that have gone through training and courses in real history, who have been trained in the academy don\u27t know how to react when we get into the public history world.
Rudy, John M.
core +1 more source

