Results 231 to 240 of about 15,539,097 (343)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Three New Philosophical Categories for Holistically Assessing Complementary Medicine, Derived from the History and Theory of Medicine.

Complement Med Res
Schmidt JM.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Is modernization widening cultural differences? [PDF]

PNAS Nexus
Talhelm T.
europepmc   +1 more source

Paediatric Medical Imaging and Radiation Therapy. [PDF]

J Med Radiat Sci
Pearn J.
europepmc   +1 more source

Real-world skin and dermatology-specific quality-of-life outcomes and a nomogram to predict skin response to secukinumab in Chinese psoriatic arthritis patients: a multicenter retrospective cohort study. [PDF]

Front Med (Lausanne)
Zhang L, Xu Z, Gong J, Tao X, Hu F.
europepmc   +1 more source

Missingness in Eligibility Criteria for Target Trial Emulation in EHR With Survival Outcomes. [PDF]

Stat Med
Shen J, Linn KA, Clark AS, Mamtani R, Hubbard RA.   +4 more
europepmc   +1 more source

Hemoperitoneum from omental variceal bleed resulting in first documented successful liver transplant: A case report. [PDF]

World J Transplant
Currier EE, Won CY, Parraga X, Lee KS, Saberi B.   +4 more
europepmc   +1 more source