Results 151 to 160 of about 18,041,803 (314)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Image Segmentation Based on World Cup Optimization Algorithm

Majlesi Journal of Electrical Engineering
Image segmentation has been widely used in different applications of the image processing. It The main objective of image segmentation is to subdivide the input images to their main components.
Mohsen Shahrezaee
doaj  

DefectAtlas-20: A real-world image dataset for joint material and surface-condition classification. [PDF]

Data Brief
Buettner R, Fischer-Brandies L, Pasold L, Eisentraut L.   +3 more
europepmc   +1 more source

World health: the magazine of the World Health Organization: May 1972 [full issue]

, 1972
35 p ...
World Health Organization
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Efficient real-world image denoising using multi-scale gaussian pyramids. [PDF]

Sci Rep
Rani A, Bhogal RK.
europepmc   +1 more source

World Health: the magazine of the World Health Organization: December 1986 [full issue]: water is development

, 1986
31 p ...
World Health Organization
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

SP-IGAN: An Improved GAN Framework for Effective Utilization of Semantic Priors in Real-World Image Super-Resolution. [PDF]

Entropy (Basel)
Wang M, Li Z, Liu H, Chen Z, Cai K.
europepmc   +1 more source

A guide to international recommendations on names and symbols for quantities and on units of measurement / D. Armstrong Lowe

, 1975
Translation of pp.263-305 available in French as: Guide pour l' utilisation du système international d' unités (SI)314 ...
World Health Organization, Lowe, D. Armstrong   +1 more
core