Results 201 to 210 of about 686,123 (339)

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

open access: yesAdvanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang   +16 more
wiley   +1 more source

AntiBMPNN: Structure‐Guided Graph Neural Networks for Precision Antibody Engineering

open access: yesAdvanced Science, EarlyView.
AntiBMPNN, a deep learning framework that integrates antibody‐specific 3D data, MPNN, frequency‐based scoring, and AlphaFold 3, achieves superior antibody sequence design. In most cases, it outperforms ProteinMPNN, AntiFold, and AbMPNN in CDR design, demonstrating higher binding affinities and sequence recovery.
Ze‐Yu Sun   +13 more
wiley   +1 more source

SYSTEMATIC EVALUATION OF A COMMERCIAL DEEP-LEARNING MODEL BASED AUTO-SEGMENTATION FOR ORGAN-AT-RISK IN A NEAR-REAL-WORLD HEAD AND NECK CANCER PATIENT DATASET

open access: diamond
Ganapathy Krishnan   +7 more
openalex   +1 more source

Implantable Ion‐Selective Organic Electrochemical Transistors Enable Continuous, Long‐Term, and In Vivo Plant Monitoring

open access: yesAdvanced Science, EarlyView.
This work explores ion‐selective organic electrochemical transistors for real‐time, long‐term potassium monitoring in the xylem sap of living trees. This bioelectronic approach provides new insights into plant physiology and has the potential to revolutionize forest, agricultural, and ecological monitoring for smarter, more sustainable plant management.
Sanggil Han   +9 more
wiley   +1 more source

The inclusion of pregnant women in research during disease outbreaks globally: A scoping review. [PDF]

open access: yesRev Lat Am Enfermagem
Williams HK   +4 more
europepmc   +1 more source

Implementation of in-house pelvic radiotherapy auto-contouring in real-world clinical practice

open access: hybrid
Luı́s Ribeiro   +14 more
openalex   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

open access: yesAdvanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen   +13 more
wiley   +1 more source

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