Results 101 to 110 of about 1,849,979 (310)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

World Bank Corporate Scorecard, April 2014

open access: yes, 2014
The World Bank Group Corporate Scorecard is designed to provide a high-level and strategic overview of the World Bank Group s performance toward achieving the two goals.
World Bank Group
core   +1 more source

India’s Frustrated Search for a Multipolar Order

open access: yes, 2023
India favours a multipolar world order. For more than seven decades, New Delhi’s policy elite have argued that such an order, in which power was distributed between several major powers, would be more stable, peaceful, and equitable, and more amenable to
Hall, Ian
core   +1 more source

The Problem of World Order in Western IR Studies

open access: yesVestnik MGIMO-Universiteta, 2016
The article "Problem of world order in modern Western studies" is the study of one of the most debated issues in the science of international relations - world order.
Maria Victorovna Soljanova
doaj  

PRESIDENT TRUMPS’ STRATEGY: CONTINUITY AND NEW APPROACHES

open access: yesVestnik MGIMO-Universiteta, 2019
After Donald Trump took office as President of the United States, Washington displays in many respects a new foreign policy philosophy, as well as non-conventional political practices.
O. V. Prikhodko, P. Ye. Smirnov
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

World Order

open access: yes, 2014
Henry Kissinger offers in World Order a deep meditation on the roots of international harmony and global disorder. Drawing on his experience as one of the foremost statesmen of the modern era advising presidents, traveling the world, observing and ...
Kissinger, Henry
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

World Development Report 1988

open access: yes, 1988
This is the eleventh report in the annual series assessing major development issues. Part I reviews recent trends in the world economy and their implications for the future prospects of developing countries. Part II examines the role of public finance in
World Bank
core   +1 more source

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