Results 141 to 150 of about 16,434,579 (300)
ClíoThe aim of the study is to analyse the cooperation of international organizations in shaping a global security strategy and countering modern threats.
Sergiy Lukin +2 more
doaj +1 more source
Homogenizing nationalists, budding fascists, and truculent exceptionalists: the end of world order in the Indo-Pacific. [PDF]
Int Polit (Hague), 2022 McKinney JM.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Legitimacy challenges to the liberal world order: Evidence from United Nations speeches, 1970-2018. [PDF]
Rev Int Organ, 2021 Kentikelenis A, Voeten E.
europepmc +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Peacemaking and International Order after the First World War
, 2023 The Paris peace settlements following the First World War remain amongst the most controversial treaties in history. Bringing together leading international historians, this volume assesses the extent to which a new international order, combining old and
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
THE HEART OF DARKNESS: TRAUMATIC INCLUSION
Russian Journal of Economics and Law, 2015 Objective: to analyze the genesis, dynamics, and prospects of destructive processes in the global community of the twenty-first century. Methods: the problem is considered in the form of narrative descript (political philosophy) using scenario ...
A. I. Nеklessa
doaj
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source