Results 71 to 80 of about 16,434,579 (300)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Russian Federation and Reshaping a Post-Cold War Order
Politeja, 2019 Russia attempts to revise a Western-led liberal world order. However, challenging the West seems to be a strategy aimed at improving Russia’s international standing.
Agnieszka Bryc
doaj +1 more source
, 2011 The little data book 2011 is a pocket edition of world development indicators 2011. It is intended as a quick reference for users of the world development indicators database, book, and CD-ROM. The database, which
World Bank
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Syria: adjusting to the new world order [PDF]
, 1997 The advent of the New World Order has challenged Syria's role in the Middle East. Traditionally viewed as a pariah state, and a Soviet satellite, Syria's future looked uncertain.
Quilliam, Neil Mason, Quilliam, N.M.
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Сравнительная политика, 2020 Proceedings of the roundtable “Regional Orders and the Rise of CHINA”, organized in the framework of the RISA Convention on October 21, 2019 at MGIMO University.
A. D. Voskressenski
doaj +1 more source
World Development Indicators 2014
, 2014 World Development Indicators 2014 provides a compilation of relevant, high-quality, and internationally comparable statistics about global development and the fight against poverty.
World Bank
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source