Pediatric clinical trials in emergency or intensive care settings using exception from informed consent and waiver of informed consent regulations. [PDF]
Yang L, Wang Y, Wang P, Xu S, Yang R.
europepmc +1 more source
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky +12 more
wiley +1 more source
Protecting infants from RSV: cost-effectiveness of nirsevimab in a real-world study from Chile. [PDF]
Priante E, Baraldi E.
europepmc +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Aging modulates amyloid clearance kinetics during anti-amyloid therapy: evidence from real-world serial amyloid PET. [PDF]
Iizuka T, Watanabe T, Kameyama M.
europepmc +1 more source
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître +7 more
wiley +1 more source
State of the nation: Understanding the current NHS treatment pathway to identify opportunities to advance future care of patients with high-risk non-muscle invasive bladder cancer in the UK (SPAN-UK). [PDF]
Aning J +9 more
europepmc +1 more source
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer +12 more
wiley +1 more source
9. Regional Study on the Characteristic Seismicity of the World : Part 4. New Britain Island Region
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