Results 121 to 130 of about 1,878,464 (266)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Esquizofrenia: quarenta anos da hipótese dopaminérgica sob a ótica da Química Medicinal
Química Nova, 2004 Schizophrenia is a devastating psychiatric illness that affects 1-2% of the world population and continues as a challenge to neuroscience. In this work, we describe an account about the historical evolution of the dopaminergic hypothesis of schizophrenia
Menegatti Ricardo +5 more
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 1949 Second World Health Assembly = Assemblée mondiale de la Santé, deuxième session1 ...
World Health Assembly, 2
core +1 more source
Results and Performance of the World Bank Group 2025 (Concept Note)
The Results and Performance of the World Bank Group 2025 (RAP 2025) report presents a two-part review of the lending and non-lending support of the World Bank Group.
World Bank
core +2 more sources
The World Bank Group Country Opinion Survey FY 2014
, 2015 The Country Opinion Survey in Senegal assists the World Bank Group (WBG) in gaining a better understanding of how stakeholders in Senegal perceive the WBG. It provides the WBG with systematic feedback from
World Bank Group
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A Renewed Framework for World Bank Engagement
Artisanal and small-scale mining (ASM) has played an increasingly active role in national development and international trade over the decades. As of 2024, those engaged directly and indirectly in the sector’s
World Bank
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Agriculture Innovation and Technology in World Bank Projects
This Evaluation Insight Note (EIN) aims to contribute to the World Bank’s goal of encouraging the use of data, digital technology, and innovation towards transforming agri-food systems in client countries. The EIN
World Bank
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