Results 151 to 160 of about 27,786,557 (299)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Group of unidentified nurses, World War I
, 1914 Black and white photograph of a group of unknown World War I nurses from the 5th Northern General Hospital, Leicester, in homemade passepartout frame. Signed 'Jessie', 'Mary', 'Betty' and 'Helen'.Digitised by the University of Leicester during February ...
Anon
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Unidentified nurse, World War I, Christmas 1917
, 1917 Black and white photograph of an unknown World War I nurse from the 5th Northern General Hospital, Leicester, in homemade passepartout frame. Mansucript inscription 'Best wishes [name unclear] Xmas 1917'.Digitised by the University of Leicester during ...
Anon
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
USA bonds - Weapons for Liberty, World War I poster
, 2018 This poster from World War I depicts a boy scout handing a sword to Liberty wrapped in an American flag while holding a shield bearing a government seal. The poster encourages the purchase of USA Bonds.U.S.A. Bonds. Third Liberty Loan Campaign BOY SCOUTS
Leyendecker, J. C. (Joseph Christian), 1874-1951, artist
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Robert Conrad during World War I, ca. 1918
, 1918 Robert Y. Conrad, Class of 1905, in World War I uniform. Captain, Company "I", 116th Infantry, 29th Division, A.E.F. Killed in action, battle of Marne, October 9, 1918. Awarded Distinguished Service Cross (posthumously.) Buried at: Plot E, Row 43, Grave
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