Results 201 to 210 of about 1,901,336 (344)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Growing up with Radicalized Parents: The Experiences of Dutch Children of NSB and SS members During and After World War II. [PDF]

open access: yesJ Child Adolesc Trauma
van der Molen M   +6 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

NEW INSIGHTS INTO DEVELOPMENT OF MATERNITY HOSPITALS IN THE REPUBLIC OF CROATIA AFTER WORLD WAR II: OUTPATIENT MATERNITY DEPARTMENT IN KLANJEC, HRVATSKO ZAGORJE, CROATIA. [PDF]

open access: yesActa Clin Croat
Fureš R   +10 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Vassili Grossman, Carnets de guerre. De Moscou à Berlin, 1941-1945

open access: yesJournal of Power Institutions in Post-Soviet Societies, 2015
Emilia Koustova
doaj  

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