Results 71 to 80 of about 13,129,311 (263)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Pre-World War II Romania from Latvian Perspective: An Envoy's views
Revista Română pentru Studii Baltice şi Nordice, 2011 :The paper approaches the working environment and observations of Latvian envoy Ludvigs Ēķis in Romania from the autumn of 1939 when the Latvian Legation was opened in Bucharest until the summer of 1940 when the State of Latvia was liquidated.
Ēriks Jēkabsons
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Review: The Lights That Failed. European International History, 1919–1933 (Zara Steiner)
Reviews in History, 2006 Review of The Lights That Failed. European International History, 1919–1933 by Zara Steiner.
Patricia Clavin
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Lviv Classical Archaeology Before World War II
Archaeologia PolonaAt the end of the 19th and the beginning of the 20th centuries, Europe experienced a period of scientific advances in various fields. This is associated with the results of numerous surveys, discoveries, accidental finds, and scientific research ...
Natalia Bulyk +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
World War II in Contemporary English-language Literature
Известия Уральского федерального университета. Серия 2: Гуманитарные наукиWorld War II remains popular in English-language literature. The article analyses novels by leading British and Australian writers dedicated to the war that were written in the second decade of the twenty-first century.
Olga Grigorievna Sidorova
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source