Results 41 to 50 of about 1,996,670 (371)

R2RML: RDB to RDF mapping language [PDF]

open access: yes, 2012
Este documento describe R2RML un lenguaje para expresar las equivalencias personalizadas desde las bases de datos relacionales a los conjuntos de datos RDF.
World Wide Web Consortium
core  

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Gli standard grafici nel world wide web

open access: yesGEOmedia, 2016
Gli standard grafici nel world wide ...
Luigi Colombo, Barbara Marana
doaj   +2 more sources

Directrius per a l'accessibilitat al contingut de pàgines web, versió 1.0 : resum

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 1999
Les Directrius per a l'accessibilitat al contingut de pàgines web tenen l'objectiu de promoure l'accessibilitat del contingut de la web per a persones amb discapacitats, però també d'ajudar a trobar la informació dins el web i facilitar-ne l'ú a tot ...
World Wide Web Consortium
doaj  

Platforms and hyper-choice on the World Wide Web

open access: yesBig Data & Society, 2018
Choice is a sine qua non of contemporary life. From childhood until death, we are faced with an unending series of choices through which we cultivate a sense of self, govern conduct, and shape the future. Nowadays, individuals increasingly experience and
Timothy Graham
doaj   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

open access: yesFEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi   +2 more
wiley   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

open access: yesFEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura   +7 more
wiley   +1 more source

Data Catalog vocabulary (DCAT) [PDF]

open access: yes, 2014
DCAT es un vocabulario RDF diseñado para facilitar la interoperabilidad entre los catálogos de datos publicados en la Web. En este documento se define el esquema y se proporcionan ejemplos para su uso. Mediante el uso de DCAT para describir conjuntos de
World Wide Web Consortium
core  

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