Results 61 to 70 of about 20,466 (193)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

El acceso a VacciMonitor puede hacerse a través de la Web of Science / Accessing VacciMonitor by the Web of Science

VacciMonitor, 2015
VacciMonitor has gradually increased its visibility by access to different databases. Thus, it was introduced in the project SciELO, EBSCO, HINARI, Redalyc, SCOPUS, DOAJ, SICC Data Bases, SeCiMed, among almost thirty well-known index sites ...
Daniel Francisco Arencibia-Arrebola, Rolando Felipe Ochoa-Azze   +1 more
doaj  

Bibliometric analysis of research on China’s rural environmental governance in CNKI and WOS

Frontiers in Environmental Science
At present, the global consensus on the concept of sustainable development continues to deepen, and China’s ecological civilization construction and rural revitalization strategy continue to advance. However, the rural environmental situation in China is
Qin Shen, Qing Sun, Aopei Zhao
doaj   +1 more source

Periódicos Científicos da Ciência da Informação: os títulos indexados na WoS

Revista Española de Documentación Científica, 2015
Este artículo estudia las revistas en el campo de Ciencias de la Información indexadas en la Web of Science (WoS). Los objetivos específicos son: a) describir las características editoriales de las revistas indexadas en la Web of Science (WoS).
Rosângela Schwarz Rodrigues, Daniela Stubert   +1 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A bibliometric analysis of budgetary slack: Insights from web of science and China National Knowledge Infrastructure using CiteSpace

Sustainable Futures
Purpose: This study conducts a comprehensive bibliometric analysis to explore the evolution and current status of research on budgetary slack, aiming to identify development trends and suggest future directions in this important field of budgeting ...
Chenfei Zhuang, Norhayati Binti Alias, Noraizah Binti Abu Bakar   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

تولیدات علمی دانشگاه آزاد اسلامی از سال 1990 تا 2007 میلادی بر اساس آمار پایگاه‌های مؤسسه اطلاعات علمی (ISI) [PDF]

کتابداری و اطلاع‌رسانی, 2010
مقاله حاضر با استفاده از آمارهای مؤسسه اطلاعات علمی (ISI)، وضعیت تولیدات علمی دانشگاه آزاد اسلامی را در سالهای 1990 تا 2007 میلادی بررسی نموده است. نویسندگان دانشگاه آزاد اسلامی بیش از 100 نوع نام متفاوت را در پایگاه WOS مؤسسه اطلاعات علمی نمایه کرده‌اند.
علی تقی زاده, اسماعیل وزیری   +1 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source