Results 71 to 80 of about 779,276 (357)

A Cerberus‐Inspired Anti‐Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging “Superbug” Yeast Candida auris

, 2020
The pathogenic yeast Candida auris has received increasing attention due to its ability to cause fatal infections, its resistance toward important fungicides, and its ability to persist on surfaces including medical devices in hospitals.
Bodenberger, N., Dietz, S., Flaig, C., Franco, O., González‐Garcia, M., Gottschalk, K., Heerde, T., Kang, F., Kissmann, A., Kubiczek, D., Otero‐González, A., Raber, H., Rosenau, F., Staendker, L., Walther, P., Weil, T., Wittgens, A.   +16 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

PENGARUH PENDIDIKAN PERAWATAN LUKA GANGREN TERHADAP KEMAMPUAN PERAWATAN LUKA MANDIRI KELUARGA DI POLI RAWAT LUKA RSK MOJOWARNO [PDF]

, 2015
Public health education seeks to realize or know how to maintain their health , how to avoid or prevent - things that harm their health and the health of others , where should seek treatment if sick , and so forth . The research problem is still a lot of
Kurniawan, Dhiyan Sandhe
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Haavanhoito-opas palvelutalon hoitohenkilökunnalle [PDF]

, 2017
Tämän opinnäytetyön tarkoituksena oli tuottaa käytännöllinen ja selkeä haavanhoito-opas palvelutalon henkilökunnalle. Tavoitteena oli kehittää ja päivittää hoitohenkilökunnan haavanhoito-osaamista ja parantaa hoidon laatua.
Siirilä, Petra-Nora, Suokas, Mirka
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evaluation of Emerging Technologies to Aid in the Detection and Diagnosis of Acute Extremity Compartment Syndrome

Diagnostics
Background/Objectives: The diagnosis of acute compartment syndrome (ACS) of the extremities is typically based on subjective clinical signs and symptoms, highlighting the need for user-friendly diagnostic tools to improve accuracy and reliability.
Catharina Gaeth, Daniel J. Cognetti, Stefanie M. Shiels, Kinton Armmer, Amber M. Powers, Robert V. Hainline, Thomas J. Walters, Robert J. Moritz   +7 more
doaj   +1 more source

Laboratory evaluation of Drawtex Hydroconductive Dressing with LevaFiber technology [PDF]

, 2014
Good wound bed preparation is an essential aspect of wound care and effective wound healing. Removal of dead and necrotic tissue either through autolytic or interventional debridement, followed by good exudate management, inhibition of matrix ...
Edwards-Jones, Valerie, School of Engineering, Manchester Metropolitan University, UK, School of Research, Enterprise and Innovation, Manchester Metropolitan University, Manchester, UK, Spruce, Pam, TVRE Consulting. Stoke on Trent, UK, Vishnyakov, Vladimir   +5 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Using honey in wound care [PDF]

, 2006
Honey is primarily a herbal product with some modifications that are made by the bees that process the nectar or sap collected from the plants to store as honey. The types of phytochemicals present in a honey depend on the plant source of the honey.
Molan, Peter C.
core   +2 more sources