Results 51 to 60 of about 1,745,201 (399)

Microfibril-associated protein 5 and the regulation of skin scar formation

Scientific Reports, 2023
Many factors regulate scar formation, which yields a modified extracellular matrix (ECM). Among ECM components, microfibril-associated proteins have been minimally explored in the context of skin wound repair.
Chen Han, Trevor R. Leonardo, Bruna Romana-Souza, Junhe Shi, Shalyn Keiser, Heidi Yuan, Mohamad Altakriti, Matthew J. Ranzer, Sammy Ferri-Borgogno, Samuel C. Mok, Timothy J. Koh, Seok Jong Hong, Lin Chen, Luisa A. DiPietro   +13 more
doaj   +1 more source

Atopic Dermatitis and Autoimmune Connective Tissue Diseases: Systematic Review and Meta-Analysis

Dermatology Practical & Conceptual
Introduction: The association between atopic dermatitis (AD) and autoimmune connective tissue diseases (ACTD) is not well-investigated. Objective: We aimed to conduct a systematic review and meta-analysis to assess the association between AD and ACTD.
Somaia Naassan, Misbah Noshela Ghazanfar, Simon Francis Thomsen, Zarqa Ali   +3 more
doaj   +1 more source

Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Case Reports in Dermatological Medicine, 2018
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body.
Astrid-Helene Ravn Jørgensen, Yiqiu Yao, Simon Francis Thomsen   +2 more
doaj   +1 more source

Functional Reconstruction of a Combined Tendocutaneous Defect of the Achilles Using a Segmental Rectus Femoris Myofascial Construct: A Viable Alternative

Archives of Plastic Surgery, 2014
The composite anterolateral thigh flap with vascularized fascia lata has emerged as a workhorse at our institution for complex Achilles defects requiring both tendon and soft tissue reconstruction.
Michael Vincent DeFazio, Kevin Dong Han, Karen Kim Evans   +2 more
doaj   +1 more source

Skin scarring: Latest update on objective assessment and optimal management

Frontiers in Medicine, 2022
Although skin scarring is considered by some to be a minor, unavoidable consequence in response to skin injury, for many patients, cosmetically unsightly scars may cause uncomfortable symptoms and loss of function plus significant psycho-social distress.
Rubinder Basson, Ardeshir Bayat, Ardeshir Bayat   +2 more
doaj   +1 more source

Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration

Pharmaceutics, 2020
Skin wound healing shows an extraordinary cellular function mechanism, unique in nature and involving the interaction of several cells, growth factors and cytokines.
E. M. Tottoli, R. Dorati, I. Genta, E. Chiesa, S. Pisani, B. Conti   +5 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

3D hybrid wound devices for spatiotemporally controlled release kinetics [PDF]

, 2012
This paper presents localized and temporal control of releasekinetics over 3-dimensional (3D) hybridwounddevices to improve wound-healing process. Imaging study is performed to extract wound bed geometry in 3D.
Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +3 more
core   +1 more source

Influence of Acidic pH on Wound Healing In Vivo: A Novel Perspective for Wound Treatment

International Journal of Molecular Sciences, 2022
There has been little understanding of acidification functionality in wound healing, highlighting the need to study the efficacy of wound acidification on wound closure and cellular activity in non-infected wounds.
Pivian Sim, X. Strudwick, Yunmei Song, A. Cowin, S. Garg   +4 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source