Results 41 to 50 of about 9,782 (221)

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Robust currents control system of wound-rotor induction motor [PDF]

, 2015
Доклад посвящен исследованию робастной системы регулирования токов электропривода с машиной двойного питания. Дается математическая модель системы регулирования токов с учетом эффекта насыщения машины по главному магнитному пути.
Ishmatov, Z. S., Polyakov, V. N., Ишматов, З. Ш., Поляков, В. Н.   +3 more
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Optimum supply for an inverter-fed cage induction motor at different load conditions [PDF]

, 2008
The effects of power supply on the energy efficiency of a form-wound cage induction motor are studied when the motor operates under light loads. The cage induction motor is modelled with the space and time discretized finite-element analysis.
Arkkio, Antero, Islam, M. Jahirul
core  

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Virtual Instruments for Detecting Rotor Faults in Induction Motors

Advances in Electrical and Electronic Engineering, 2004
Rotating electrical machines play an important role in the world´s industrial life. Hence there is a demand on their reliable and safe operation. Their faults and failures can lead to excessive downtimes and generate enormous costs in reduced output ...
Lorand Szabo, Jeno Barna Dobai, Karoly Agoston Biro   +2 more
doaj  

Analisis perbandingan arus starting motor induksi 3 fasa

Jurnal Eltek
Motor induksi tiga fasa merupakan motor yang mengubah energi listrik menjadi energi mekanik dan banyak digunakan pada industri kecil maupun besar sebagai penggerak.
Linda Sartika, Abdul Muis Prasetia, Muhammad Allriz Akbar   +2 more
doaj   +1 more source

Unified Direct-Flux Vector Control for AC Motor Drives [PDF]

, 2010
The paper introduces a Unified Direct-Flux Vector Control scheme suitable for sinusoidal AC motor drives. The AC drives considered here are Induction Motor, Synchronous Reluctance and synchronous Permanent Magnet motor drives, including Interior and ...
Bojoi, R., Guglielmi, Paolo, Pellegrino, Gian-Mario Luigi   +2 more
core   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Concurrently Achieving 4.6 W/M2 and 120,000 Cyclability Enabled by Extendable Swing Arms in Rotational Triboelectric Nanogenerator

Advanced Science, EarlyView.
A rotational energy harvesting device that successfully reconciles high power density with mechanical durability through a hybrid sliding‐and‐bouncing kinematic mechanism is reported. The success reported in our paper includes addressing a dilemma where enhanced electrical output comes at the cost of increased friction and wear, limiting the practical ...
Yihong Lin, Jiaming Zhou, In‐Yong Suh, Eunjong Kim, Kin Chiu Yip, Dae‐jin Kim, Jang‐Mook Jeong, Young‐Jun Kim, Jinyoung Jeon, Ju‐Hyuck Lee, Yoon‐Hwae Hwang, Sang‐Woo Kim, Dong‐Myeong Shin   +12 more
wiley   +1 more source