Results 161 to 170 of about 83,304 (314)

Single‐Chain Anti‐IL‐1β Antibody Carried by Outer Membrane Vesicles of Bacteroides fragilis Alleviates Tubular Inflammation in Chronic Kidney Disease

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Engineered Bacteroides fragilis outer membrane vesicles carrying anti‐IL‐1β scFv and kidney‐targeting peptides alleviate renal inflammation and injury in CKD mouse models via precise delivery and NF‐κB inhibition. ABSTRACT Microinflammation is a key driver of chronic kidney disease (CKD) progression, with interleukin‐1β (IL‐1β) playing a pivotal role ...
Liang Li   +6 more
wiley   +1 more source

Inertial energy storage hardware definition study (ring rotor) [PDF]

open access: yes
Rotor analysis, interference stresses, fabrication/assembly, failure analysis, ring tolerances, stren plots, and drawings are ...
Evans, H. E., Kirk, J. A.
core   +1 more source

Endothelium‐Treg Communication Through Extracellular Vesicle Transfer Exacerbates Acute Respiratory Distress Syndrome

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Here, we reveal that pulmonary endothelium‐derived EVs aggravate lung inflammation via destabilizing Tregs during ALI/ARDS. Mechanistically, Tregs absorbs EV‐Med1, which promotes the secretion of IL‐21. This cytokine in turn induces hyper‐phosphorylation of STAT3 in Tregs thus induing loss of Foxp3, creating an hyperinflammatory ALI/ARDS ...
Xu Liu   +13 more
wiley   +1 more source

Mitochondrial Intercellular Transfer via Platelets After Physical Training Exerts Neuro‐Glial Protection Against Cerebral Ischemia

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Treadmill training protects against white matter injury and reduces cerebral infarction. Muscle‐derived mitochondrial transfer via platelets is promoted by treadmill training. Platelet transfusion emerges as a potential low‐risk therapeutic strategy for sequelae and vascular dementia.
Toshiki Inaba   +8 more
wiley   +1 more source

Development of a Physiologically Based Model of Bilirubin Metabolism in Health and Disease and Its Comparison With Real‐World Data

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Bilirubin is a breakdown product of erythrocytes and plays a crucial role in elimination of heme‐containing proteins. After its synthesis in the reticuloendothelial system, unconjugated bilirubin is released into plasma and taken up into the liver.
Ahenk Zeynep Sayin, Lars Kuepfer
wiley   +1 more source

Micromanufacturing Process of Complex 3D FeCo Core Microwindings for Magnetic Flux Modulation in Micromotors. [PDF]

open access: yesMicromachines (Basel)
Diez-Jimenez E   +9 more
europepmc   +1 more source

LINC00973/DTX3L Axis Promotes Non‐Small Cell Lung Cancer Progression and Serves as a Therapeutic Target

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
LINC00973 promotes NSCLC progression by interacting with DTX3L, leading to activation of the AKT signaling pathway. Therapeutically, LINC00973 can be targeted by siRNA delivery strategies, including engineered exosomes for in vitro inhibition and in vivo self‐assembly of siRNAs within endogenous liver‐derived exosomes, thereby offering a potential ...
Yanke Chen   +15 more
wiley   +1 more source

Biology, Detection, and Management of Lecanosticta acicola: Emerging Challenges for the Management of Brown Spot Needle Blight in Pine Forests

open access: yesForest Pathology, Volume 56, Issue 1, February 2026.
ABSTRACT Brown spot needle blight (BSNB), caused by the fungus Lecanosticta acicola, is a widely distributed foliar disease of pines that causes needle necrosis, premature defoliation, and growth loss in both natural forests and commercial plantations. Although L.
Gabriel Silva   +13 more
wiley   +1 more source

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