Human Wounds and Its Burden: An Updated Compendium of Estimates [PDF]
Significance: A 2018 retrospective analysis of Medicare beneficiaries identified that ∼8.2 million people had wounds with or without infections. Medicare cost estimates for acute and chronic wound treatments ranged from $28.1 billion to $96.8 billion ...
Sen, Chandan K.
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Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds. [PDF]
Chronic wounds represent a large and growing disease burden. Infection and biofilm formation are two of the leading impediments of wound healing, suggesting an important role for the microbiome of these wounds.
Chen, Irene A+4 more
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Penetrating injuries in dogs and cats: a study of 16 cases [PDF]
The objective of this retrospective study was to assess radiographical and surgical findings, surgical management and outcome of penetrating injuries in dogs and cats by evaluating patient records.
De Rooster, Hilde+3 more
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Localization of tenascin in human skin wounds [PDF]
A total of 56 surgically treated human skin wounds with a wound age between 8h and 7 months were investigated. Tenascin was visualized by immunohistochemistry and appeared first in the wound area pericellularly around fibroblastic cells approximately 2 ...
A Maier+24 more
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Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds [PDF]
We analyzed the distribution of fibronectin in routinely embedded tissue specimens from 53 skin wounds and 6 postmortem wounds. In postmortem wounds a faint but focal positive staining was exclusively found at the margin of the specimens which dit not ...
A Nerlich+43 more
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Determined to die! Ability to act following multiple self-inflicted gunshot wounds to the head. The cook county office of medical examiner experience (2005-2012) and review of literature [PDF]
Cases of multiple (considered 2+) self-inflicted gunshot wounds are a rarity and require careful examination of the scene of occurrence; thorough consideration of the decedent’s psychiatric, medical, and social histories; and accurate postmortem ...
Barnes+15 more
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Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses. [PDF]
Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic,
Aristizobal, Fabio A+11 more
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The time-dependent expression of keratins 5 and 13 during the reepithelialization of human skin wounds [PDF]
The time-dependent reepithelialization of 55 human surgical skin wounds with a wound age between 8h and more than 2 months was investigated by the immunohistochemical localization of cytokeratins 5 and 13.
A. Nerlich+25 more
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An observational prospective study of topical acidified nitrite for killing methicillin-resistant Staphylococcus aureus (MRSA) in contaminated wounds [PDF]
Background Endogenous nitric oxide (NO) kills bacteria and other organisms as part of the innate immune response. When nitrite is exposed to low pH, NO is generated and has been used as an NO delivery system to treat skin infections.
A Ghaffari+30 more
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The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]
In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
A Martinez-Hernandez+26 more
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