Results 271 to 280 of about 992,812 (310)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

A Novel Murine Model for Studying Impaired Wound Healing in Diabetes. [PDF]

Int Wound J
Longfield MSG, Fox SL, Lourdesamy JS, Huang C, Siwan E, Parry S, Wang X, Boughton P, Min D, Twigg SM.   +9 more
europepmc   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Gas plasma therapy of murine and human diabetic wounds is associated with junctional and hippo signaling and oxidative protein modifications. [PDF]

Redox Biol
Schmidt A, Wende K, Kantz L, von Woedtke T, Bekeschus S.   +4 more
europepmc   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Hyperbaric Oxygenation of an Ozone-Containing Steam-Water Mixture as Treatment of Infected Combat Wounds of the Limbs With Antibiotic-Resistant Microflora. [PDF]

Int Wound J
Kostyliev MV, Terekhov HV, Furmanov OY, Hryhorieva NY, Savytska IM, Symulyk YV, Smitiukh LA.   +6 more
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Non-invasive Resonance Raman Spectroscopy provides an early estimation of depth in a pig model of multi-depth burns. [PDF]

J Transl Med
Jain R, Berkane Y, Ajenu EO, Nguyen KT, Shamlou AA, Muzikansky A, Cornacchini J, Lellouch AG, Uygun BE, Cetrulo CL, Randolph MA, Uygun K, Romfh P, Tessier SN.   +13 more
europepmc   +1 more source

Platelet-Rich Plasma (PRP) and Recombinant Growth Factor Therapies in Cutaneous Wound Healing: Mechanisms, Clinical Applications, and Future Directions. [PDF]

J Clin Med
Ahmed AB, Thatcher S, Khorsandi J, Ahmed Z, Lee M, Jaouhari A, Bond B, Merchant A.   +7 more
europepmc   +1 more source