Results 41 to 50 of about 814,933 (365)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

EFFECT OF NOVEL OINTMENT COMPOSITION AG/TAGA: CHITOSAN-GEL ON HEALING OF EXPERIMENTAL WOUNDS WITH DIFFERENT ORIGINS

Бюллетень сибирской медицины, 2016
The purpose of the study – evaluation of the regenerating activity of two-component paste, consisting of silver containing finely particulate sorbent: chitosan gel.Material and methodologies.
T. V. Popova, T. G. Tolstikova, A. Yu. Letyagin, N. A. Zhukova, N. P. Bgatova, L. N. Rachkovskaya, A. A. Kotlyrova, V. A. Burmistrov   +7 more
doaj   +1 more source

Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds [PDF]

, 1992
We analyzed the distribution of fibronectin in routinely embedded tissue specimens from 53 skin wounds and 6 postmortem wounds. In postmortem wounds a faint but focal positive staining was exclusively found at the margin of the specimens which dit not ...
A Nerlich, A Vaheri, A. Nerlich, AE Postlethwaite, DF Mosher, E Boehm, E Linder, E Ruoslahti, E Ruoslahti, EA Jaffee, F Grinnell, F Grinnell, F Jilek, H Hormann, H Hormann, I. Wiest, J Raekallio, J Raekallio, J Viljanto, J. Tübel, J. Wilskel, K Alitalo, KM Yamada, LA Repesh, M Kurkinen, M Oehmichen, M Oehmichen, MW Mosesson, P Betz, P Davison, P. Betz, R Jarecki, R. Penning, RAF Clark, RAF Clark, S Berg, S Berg, S Berg, S Stenman, SM Hsu, St Niewiarowski, V Schneider, W Eisenmenger, W. Eisenmenger   +43 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Experiences of Type 2 Diabetes Mellitus Patients with Nonhealing Wounds in Ghana [PDF]

, 2017
I traveled to Ghana, Africa in the summer of 2016 to study diabetic wounds at Komfo Anokye Teaching Hospital (KATH) in the city of Kumasi. Ghana is transforming from a developing nation to a middle-income nation.
Barker, Lauren
core   +2 more sources

Determined to die! Ability to act following multiple self-inflicted gunshot wounds to the head. The cook county office of medical examiner experience (2005-2012) and review of literature [PDF]

, 2015
Cases of multiple (considered 2+) self-inflicted gunshot wounds are a rarity and require careful examination of the scene of occurrence; thorough consideration of the decedent’s psychiatric, medical, and social histories; and accurate postmortem ...
Barnes, Cina, Di Maio, Heard, Hejna, Karger, Karger, Karger, Kittirattanapaiboon, Kohlmeier, Lacassagne, Ling, Oehmichen, Oehmichen, Pollak, Varnik   +15 more
core   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

A Descriptive Study of the Clinical Presentation, Management, and Outcome of Horses with Acute Soft Tissue Trauma of the Tarsus and the Association with Synovial Involvement

Animals, 2022
The tarsus is one of the most common areas of traumatic injury with associated synovial involvement (SI) in horses. The aim of this retrospective study was to describe the clinical presentation, diagnostic procedures, management (emphasizing the type ...
Taja Vajs, Omid Nekouei, Nora M. Biermann   +2 more
doaj   +1 more source

Understanding methods of wound debridement [PDF]

, 2014
Autolytic debridement describes the body's natural method of wound-bed cleansing, helping it to prepare the wound bed for healing. In acute wounds, autolytic debridement occurs automatically and often does not require intervention, as during the ...
Broadus C, Leak K, Ousey K, Ousey K, Strohal R, World Union of Wound Healing Societies (WUWHS)   +5 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source