Results 171 to 180 of about 2,839,275 (388)

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

open access: yesArthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar   +12 more
wiley   +1 more source

Effects of Dalcroze Eurhythmics Exercise Versus Multicomponent Exercise on Physical and Cognitive Function, and Falls in Older Adults: The EPHYCOS Randomized Controlled Trial

open access: yesAdvanced Biology, EarlyView.
In this randomized clinical trial conducted among 142 community‐dwelling older adults at high risk for falls over 12 months, a Dalcroze Eurhythmics exercise intervention (once weekly, group‐based) improved a variety of physical and cognitive/executive function outcomes compared with a multicomponent exercise intervention (twice weekly, group‐ and home ...
Mélany Hars   +7 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

National estimates of non-fatal firearm related injuries other than gunshot wounds [PDF]

open access: bronze, 2000
Jennifer M. Hootman   +4 more
openalex   +1 more source

Increased serum levels of procollagen type III peptide in severely injured patients [PDF]

open access: yes, 1993
Objectives: To determine the serum concentrations of procollagen type in peptide in severely injured patients with different outcomes and to evaluate the relationship between serum procollagen type III peptide concentrations, sources of increased ...
Duswald, Karl-Heimo   +6 more
core  

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

Closed trauma of the pancreas

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Closed trauma of the pancreas is a rare condition. The organ is located in a place with a relative protection. It is considered that between 1 and 5 % of serious abdominal traumatisms present a pancreatic lesion, according to different authors.
Jaime Landell Cruz   +1 more
doaj  

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

open access: yesAdvanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy