Results 121 to 130 of about 7,217,648 (295)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Increasing Cultural Participation: An Audience Development Planning Handbook for Presenters, Producers and Their Collaborators [PDF]
, 2001 Looks at how people-centered strategies for building public participation in high-quality arts programs can help institutions of varied disciplines and sizes to diversify, broaden, and deepen relationships with their ...
Marcelle Hinand Cady, Paul Connolly
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Transdisciplinary Study of Hedging Strategy in Evaluative Academic Discourse
Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 2. ÂzykoznanieThe article presents the research into hedges and hedging strategy realization in evaluative academic genres viewed from a transdisciplinary perspective.
Elena Yu. Viktorova
doaj +1 more source
Whose story is it anyway? The ethics of narration and the narration of ethics in Summertime and Die Sneeuslaper [PDF]
, 2013 Includes bibliographical references.This dissertation analyses and compares the narrative strategies in J.M. Coetzee’s Summertime and Marlene van Niekerk’s Die sneeuslaper and considers the implications of these strategies for the authors’ exploration of
Holtzhausen, Janita
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Information and Experience in Metaphor: A Perspective From Computer Analysis [PDF]
, 1986 Novel linguistic metaphor can be seen as the assignment of attributes to a topic through a vehicle belonging to another domain. The experience evoked by the vehicle is a significant aspect of the meaning of the metaphor, especially for abstract metaphor,
Russell, Sylvia Weber
core +2 more sources