Results 131 to 140 of about 7,217,648 (295)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Research priorities in limb and task-specific dystonias [PDF]

, 2017
Altenmüller, Eckart, Alter, Katharine, Alterman, Ron L, Chen, Robert, Frucht, Steven, Furuya, Shinichi, Hallett, Mark, Jankovic, Joseph, Jinnah, H.A., Kimberley, Teresa J, Lungu, Codrin, Perlmutter, Joel S, Prudente, Cecilia N, Richardson, Sarah Pirio   +13 more
core   +2 more sources

TEACHING AND LEARNING PROCESS TO IMPROVE READING SKILLS FOR THE FIFTH GRADE STUDENTS OF SD NEGERI 11 NGRINGO, JATEN, KARANGANYAR [PDF]

, 2009
This final project report is written based on the job training that which was carried out by the writer at SD Negeri 11 Ngringo, Jaten. The purposes of the project are to describe the process, method and the problems and the solution in teaching and ...
Nurhidayah, Anik
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Know Your Audience: Middlebrow aesthetic and literary positioning in the fiction of P.G. Wodehouse [PDF]

, 2016
This essay strives to explain Wodehouse’s status as a popular writer, whose work is read with enjoyment by academics, critics and the general reader alike, as resulting from his particular positioning within the literary field, scrutinizing his ...
Einhaus, Ann-Marie
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effluent limits, ambient quality, and monitoring [PDF]

, 2013
Effluent limits are frequently based on a uniform emission standard, which applies to all polluting facilities within in a single industry. However, the implementation of many environmental protection laws does not lead to uniform effluent limits due ...
Arguedas, Carmen, Earnhart, Dietrich, Rousseau, Sandra   +2 more
core   +1 more source

The migrant voice : the politics of writing home between the Sinophone and Anglophone worlds

, 2017
This paper addresses the politics of language, identity, and diasporic Chinese writing in old and emerging Chinese migrant literature. I opt for the idea of a “migrant subject” as brought up by Ha Jin to underscore a diverse verbal strategy and mobile ...
NG, Kenny K. K.
core