Results 241 to 250 of about 1,223,444 (316)

The inspiration of methyltransferase in RNA methylation modification for targeted therapy of malignant tumors. [PDF]

Front Immunol
Chen X, Liu X, Xu J, Zhu X, Liu B, Yang X, Cong G, Lin X, Chong W, Chen H.   +9 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Ten simple rules for leading a many-author non-empirical paper. [PDF]

PLoS Comput Biol
Weissgerber TL, Drude N, Rahal RM, Kohrs FE.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Regulation of RNA methylation linked to drug resistance in gastric cancer. [PDF]

Front Cell Dev Biol
Yang Z, Ma Y, Xu Z, Liu H, Gu X, Sun J.
europepmc   +1 more source

Variation and change in pronominal address in 19th and early 20th-century German private letters. [PDF]

J Hist Socioling
Schiegg M, Elspaß S.
europepmc   +1 more source

The Concurrent and Longitudinal Contributions of Linguistic and Cognitive Skills to L2 Writing Quality. [PDF]

J Intell
Zhao A, Chen F, Li X.
europepmc   +1 more source

Dynamic Assessment as a Self-Regulation Strategy in the Acquisition of Textual Revision. [PDF]

Behav Sci (Basel)
Arias-Gundin O, Rodríguez C, Fidalgo R.
europepmc   +1 more source

Self-efficacy and self-regulated learning strategies as significant predictors of english writing proficiency in Chinese EFL senior high school students. [PDF]

PLoS One
Chen X, Yan J, Guo W.
europepmc   +1 more source