Results 241 to 250 of about 131,248 (294)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Assessing Textbook Oncologic Outcomes in Distal Pancreatectomy for Pancreatic Adenocarcinoma: A National Cancer Database Study. [PDF]

J Clin Med
Alnajar A, Sleeman JD, Nerez EZ, Akcin M, Sleeman D, Kutlu O.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Classroom interaction and second language grit as predictors of college English achievement: the mediating role of learners' foreign language emotions. [PDF]

Front Psychol
Lu Q, Du Y, Zhai C, Liu W, Xu J.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Growth mindset and student writing feedback literacy among Chinese learners of Japanese: the mediating role of achievement goals. [PDF]

Front Psychol
Chen X, Bai X, Li L, Liu X.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

The role of personal and psychological, social and environmental factors in determining physical activity in Turkish school-aged adolescents: in the context of a socio-ecological model. [PDF]

Front Psychol
Çifçi F, Demir A.
europepmc   +1 more source

Leverage Points for Wellbeing and Achievement in Vocational Education: A Network Analysis of Psychological Factors Across Gender and Majors. [PDF]

Behav Sci (Basel)
Likhanov M, Fillon A, Demolliens M, Robert A, Darnon C, Huguet P, ProFAN Consortium, Régner I.   +7 more
europepmc   +1 more source

Clinical and socioeconomic determinants of glycaemic control derived from continuous glucose monitoring in adults with type 1 diabetes. [PDF]

Front Endocrinol (Lausanne)
Mesa Díaz ÁM, Rodríguez de Vera Gómez P, Ruiz Rodríguez M, Belmonte Lomas S, Gómez Zaragoza B, Mayoral Sánchez E, Martínez Brocca MA.   +6 more
europepmc   +1 more source