Results 201 to 210 of about 4,584,716 (343)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Stratospheric wave predictability enhances surface forecasts over North America. [PDF]

Sci Adv
Ding X, Xiang B, Chen G, Wang L.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Positive Affect and Academic Skill Development Through ChatGPT in Higher Education. [PDF]

Eur J Investig Health Psychol Educ
Thango BA, Matshaka L, Azazz AMS, Elshaer IA.   +3 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Fiscal Year 2010

, 2010
Annual report of the Texas Skill Standards Board describing goals, activities, and accomplishments during fiscal year ...
Texas Skill Standards Board
core  

Maintaining Paediatric Resuscitation Readiness: A Clinical Teacher's Toolbox for Low-Dose, High-Frequency Practice. [PDF]

Clin Teach
Lilitwat W.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

'The Rainbow Bridge': Writing and Teaching in a Regional Context

, 2010
This discussion explores how place shapes the teaching of creative writing. More specifically, the paper considers how creative writing can be taught within a regional context where students may have limited access to literary knowledge, traditions and ...
Green, Stephanie
core  

Longitudinal Clinical Debrief in an Undergraduate Medical Programme. [PDF]

Clin Teach
Harris S, Drovandi A, Tahir S, Merrifield S.   +3 more
europepmc   +1 more source