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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Impact of patient-based teaching in improving prescription writing skills of II MBBS students.
Int J Appl Basic Med Res, 2016 Thenrajan P, Murugan PR.
europepmc +1 more source
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Nursing Standard, 2003
This article offers students on diploma and degree courses a constructive step-by-step guide to planning, writing and critically reviewing their module assignment papers. Guidance is accompanied by a selection of practical activities designed to enhance students' information gathering and assignment writing skills.
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This article offers students on diploma and degree courses a constructive step-by-step guide to planning, writing and critically reviewing their module assignment papers. Guidance is accompanied by a selection of practical activities designed to enhance students' information gathering and assignment writing skills.
openaire +2 more sources
2021
Designed specifically for UQ College students, this Pressbook offers interactive activities and strategies for developing academic writing skills. Students will have the opportunity to review key parts of the writing process from interpreting their assignment instructions, organizing their ideas, drafting their writing, and revising their work before ...
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Designed specifically for UQ College students, this Pressbook offers interactive activities and strategies for developing academic writing skills. Students will have the opportunity to review key parts of the writing process from interpreting their assignment instructions, organizing their ideas, drafting their writing, and revising their work before ...
openaire +1 more source
This article investigates the development of writing skills across different age groups, analyzing the cognitive, social, and emotional factors that influence writing ability in children, adolescents, and adults. It examines the stages of writing development, the impact of age on writing fluency, creativity, and complexity, and the role of motivation ...
Ramazonova, F.A., Ruzmatova, Laylo
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Ramazonova, F.A., Ruzmatova, Laylo
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