Results 101 to 110 of about 2,751,301 (289)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Standardized testing and written communication improve patient understanding of beta-lactam allergy testing outcomes: A multicenter, prospective study. [PDF]

open access: yesJ Allergy Clin Immunol Glob, 2022
Loprete J   +17 more
europepmc   +1 more source

Where We May Oftener Converse Together : Translation of Written and Spoken Communication in Colonial Pennsylvania

open access: yes, 2016
In this paper I examine the differences between colonists’ and Indians’ perceptions and use of language in early Pennsylvania. Through consideration of translation challenges in both spoken and written contexts, I conclude that while residents of the ...
Fleming, Jenna E.
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

CONTENT OF TEACHING PROFESSIONALLY ORIENTED WRITTEN COMMUNICATION

open access: yesNovìtnâ Osvìta, 2016
The article is devoted to the problems of teaching foreign languages in non-linguistic universities in the process of professional education. Special attention is paid to teaching professionally oriented written communication in English and developing ...
I. I. Antonenko
doaj   +1 more source

The effect of the MNB’s communication on financial markets [PDF]

open access: yes
Our paper aims to assess how the Magyar Nemzeti Bank’s communication affects financial asset prices. We find that the central bank plays the most important role in influencing long-term yields.
Klára Pintér, Péter Gábriel
core  

Generating a 3D Simulation of a Car Accident from a Written Description in Natural Language: the CarSim System [PDF]

open access: yes, 2001
This paper describes a prototype system to visualize and animate 3D scenes from car accident reports, written in French. The problem of generating such a 3D simulation can be divided into two subtasks: the linguistic analysis and the virtual scene ...
Dupuy, Sylvain   +3 more
core   +2 more sources

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