Results 51 to 60 of about 468,667 (249)

Um modelo para o parecer psiquiátrico no hospital geral A model for the written report in consultation-liaison psychiatry

open access: yesJornal Brasileiro de Psiquiatria, 2006
OBJETIVO: Propor um modelo estruturado para a elaboração das respostas às solicitações de pareceres psiquiátricos no hospital geral e discutir seus aspectos fundamentais. MÉTODOS: Foi realizada uma pesquisa sistemática nas bases de dados PubMed/Medline e
Antonio Leandro Nascimento   +3 more
doaj   +1 more source

Developing Mathematics Written Communication through Case-Based Learning

open access: yesJTAM (Jurnal Teori dan Aplikasi Matematika), 2023
Mathematical education, as it is now practiced, has many problems. Students that were taught using traditional instruction were only taught to listen. Without the input and feedback of the pupils, the teacher controls the learning process.
Joko Suratno   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

أثر النص التمثيلي في تنمية مهارات التواصل اللغوي لدى تلاميذ الصف الخامس الابتدائي [PDF]

open access: yesمجلة البحث العلمي في التربية, 2019
هدفت هذه الدراسة إلى تعرف أثر النص التمثيلي في تنمية مهارات التواصل اللغوي لدى تلاميذ الصف الخامس الابتدائي، وقد استخدم الباحث المنهج التجريبي في تصميمه شبه التجريبي القائم على مجموعتين: تجريبية وضابطة، وتکون مجتمع الدراسة من جميع تلاميذ الصف الخامس ...
نايف مقعد مصلح العتيبي
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Analysis of students' writing ability using concept maps based on Dienes’ theory

open access: yesResearch and Development in Education
As one of the important aspects in learning, both written and oral, communication is obtained from how students express their ideas. One of them is by using a concept map that is compiled using relevant theoretical references.
Alfiani Athma Putri Rosyadi   +3 more
doaj   +1 more source

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