Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Concurrent pulmonary candidiasis and tuberculosis in type 2 diabetes mellitus: immune pathogenesis and multidisciplinary management challenges: a case report. [PDF]
Zheng A +6 more
europepmc +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Solitary giant abscess extending from the left gluteal to thigh due to Nocardia cyriacigeorgica in an immunocompetent patient: a case report. [PDF]
Li W, Wang Z, Li Y, Zhang F, Zhuang Q.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Combined itraconazole and terbinafine therapy for pediatric kerion: a report of two cases. [PDF]
Ma D, Lu Y, Fang F, Zhou H, Liu X.
europepmc +1 more source
Culture-Negative Infective Endocarditis Presenting With Cardio-Hepatorenal Syndrome in a 21-Year-Old Patient: A Case Report of Diagnostic Workup and Management. [PDF]
Kotaich J +6 more
europepmc +1 more source
Exploring Culture through Literature Written in Unfamiliar Languages
Lisa Thomas, Kathy G. Short
doaj
Development of a Rotational Culture Method for Reconstruction of Mesodermal Tissue: A Preliminary Study. [PDF]
Kobayashi S +7 more
europepmc +1 more source

