Results 91 to 100 of about 583,690 (214)
The Contribution of Verbal Working Memory to Deaf Children's Oral and Written Production. [PDF]
Arfé B, Rossi C, Sicoli S.
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
L’apport de La Lecture à La production Écrite
The Contribution of Reading to the Written Production In our modern society, writing occupies a prominent place in Arabic first and then in FFL. In fact, writing serves us in our daily lives: shopping list, email writing, exam, writing, copy, of a ...
Fatiha Bouazri
doaj
Does segmental overlap help or hurt? Evidence from blocked cyclic naming in spoken and written production. [PDF]
Breining B, Nozari N, Rapp B.
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Phonological codes constrain output of orthographic codes via sublexical and lexical routes in Chinese written production. [PDF]
Wang C, Zhang Q.
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Les erreurs grammaticales dans les productions écrites des apprenants à l’ école primaire: causes et remédiations [PDF]
In Burkina Faso, French is both a subject and a vehicle for education. In primary school, its teaching in written form begins in elementary school with the observation of inadequacies in the learners’ written productions, in particular the incorrect ...
Ahoubahoum Ernest PARDEVAN
doaj

