Results 61 to 70 of about 10,478 (225)

Utilization of Proteomic Measures for Early Detection of Drug Benefits and Adverse Effects

The Journal of Clinical Pharmacology, EarlyView.
Abstract Recognition of benefits and adverse effects of therapies in earlier clinical trial phases could improve the safety, efficiency, and cost of clinical trials. Using four clinical trials representing a diverse set of diseases and drug classes (EXSCEL: exenatide/GLP‐1 RA, SUGAR‐DM‐HF: empagliflozin/SGLT2i, PRADA: epirubicin/anthracycline, and ...
Jessica Chadwick, Colin Berry, Meredith A. Carpenter, Geeta Gulati, Siri Lagethon Heck, Michael A. Hinterberg, Rury R. Holman, Matthew M.Y. Lee, Torbjørn Omland, Clare Paterson, Mark C. Petrie, Naveed Sattar, Svati H. Shah, Sama Shrestha, Harald Sourij, Emma V Troth, Victoria Vinje, Stephen A. Williams   +17 more
wiley   +1 more source

Guidance for umbrella reviews of observational studies: A scoping review

JCPP Advances, EarlyView.
This review examined existing guidance on conducting and reporting umbrella reviews of observational studies on epidemiological associations, aiming to help develop a formal reporting guideline. The search identified 4491 records, with eight documents providing limited guidance across seven topic areas.
Carl Zhou, Nicholas Fabiano, Arnav Gupta, Stanley Wong, Kelly D. Cobey, David Moher, Sanam Ebrahimzadeh, Jeremy Y. Ng, Elena Dragioti, Jae Il Shin, Joaquim Radua, Samuele Cortese, Beverley Shea, Nicola Veronese, Lisa Hartling, Michelle Pollock, Stefania Papatheodorou, John P. A. Ioannidis, Marco Solmi   +18 more
wiley   +1 more source

School experiences and self‐harm in the OxWell study

JCPP Advances, EarlyView.
Understanding which school experiences are associated with greater self‐harm. More support is needed for girls and gender diverse populations. Many school experiences are things we can address and change, such as bullying. Abstract Background Schools are key for identifying challenges faced by young people who self‐harm (SH).
Rasanat Fatima Nawaz, Tamsin Jane Ford, Mina Fazel, Galit Geulayov, The OxWell Study Team, Simon R. White   +5 more
wiley   +1 more source

Validation and use of the dead‐end ultrafiltration method for the capture and recovery of Shiga toxin‐producing Escherichia coli from surface water

Journal of Environmental Quality, EarlyView.
Abstract Root cause analysis following microbial water contamination events typically relies upon the collection of large sample volumes. Dead‐end ultrafiltration (DEUF) is an efficient method for sampling and transporting up to 100 L of water from field environments. A single‐lab validation (SLV) using DEUF to recover Shiga toxin‐producing Escherichia
Ai Kataoka, Jennifer L. Wolny, Jose Roberto Guzman, Andrew Battin, Shizhen S. Wang, Rebecca Zaayenga, Phillip Kuri, Julie A. Kase   +7 more
wiley   +1 more source

Working together to ensure research conducted with Aboriginal and/or Torres Strait Islander Peoples is culturally appropriate illustrated using a pharmacy‐intervention study

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Historically, health research conducted in Australia with Aboriginal and/or Torres Strait Islander Peoples has not been requested by communities. Health policies cite evidence for inclusive care including cultural perspectives.
Susan Welch, Gemma Purcell‐Khodr, Pauline Deweerd, Rebekah Moles, Alexander Viardot, Scott Daly, Kylie Lee   +6 more
wiley   +1 more source

Intrasheath Tendon Subluxation Beyond the Ankle

Journal of Ultrasound in Medicine, EarlyView.
Peroneal tendon intrasheath subluxation is a well‐established phenomenon in musculoskeletal ultrasound. However, until now, intrasheath tendon subluxation has not been described in the hand. This unique case series presents the first three reported cases of intrasheath tendon subluxation in the hand.
Hannah Lamberg, Molly N. Pantelic, Erika Mojica, Heidi Ehrich, Dana Rowland, Shannon Wood, Gunjan Malhotra, Steven B. Soliman   +7 more
wiley   +1 more source

Effectiveness of Carbon Dioxide Cryotherapy for the Treatment of Localized Cutaneous Leishmaniasis in Ethiopia

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Cutaneous leishmaniasis (CL) is a public health problem in Ethiopia. Diagnosis is often delayed, and treatment options are limited. Liquid nitrogen cryotherapy is a recommended treatment but not widely available. Carbon dioxide (CO2) cryotherapy is used for the prevention of cervical cancer and is widely available in Ethiopia and ...
Feleke Tilahun Zewdu, Saba Maria Lambert, Michael Marks, Yematawork Kebede Aragaw, Derese Bekele Daba, Kassahun Alemu, Endalamaw Gadisa, Stephen L. Walker   +7 more
wiley   +1 more source

Hematopoietic Stem Cell Transplantation in an International Cohort of Colony Stimulating Factor‐1 Receptor (CSF1R)‐Related Disorder

Movement Disorders, EarlyView.
Abstract Background Colony stimulating factor‐1 receptor (CSF1R)‐related disorder (CSF1R‐RD) is an autosomal dominant, rapidly progressive, demyelinating disease leading to death usually within a few years. Because of the central role of CSF1R in microglia functions, allogeneic hematopoietic stem cell transplantation (HSCT) has been suggested as a ...
Hemmo A.F. Yska, Marianne Golse, Shanice Beerepoot, Stefanie Hayer, Caroline Bergner, Anderson Rodrigues Brandao de Paiva, Cecilia Marelli, Natalia Julia Palacios, Yudy Llamas Osorio, Camille Huiban, Georg Franke, Friederike Wortmann, Udo Holtick, Xavier Ayrignac, Marjo S. van der Knaap, Ludger Schöls, Vincent Perlbarg, Damien Galanaud, Moniek A. de Witte, Nicole I. Wolf, Stéphanie Nguyen, Fanny Mochel, the International CSF1R‐RD Working Group, Wolfgang Köhler, Angeles Garcia‐Cazorla, Laetitia Souchet, Boris Chaumette, Bernardo Blanco, Magali Barbier, Bruno Stankoff, Anne‐Laure Dubessy, Florence Robert‐Varvat, Audrey Riou, Sacha Weber, Benjamin Bender, Nathalie Fegueux, Patrice Ceballos, Nicolas Menjot de Champfleur, Sylvain Lehmann, Clarisse Cara‐Dallière, Pierre Labauge, Caroline Lindemans, Fernando Freua, Livia Mariano, Leandro Tavares Lucato, Gustavo Bruniera Peres Fernandes, Claudio M. de Gusmão, José Ulysses Amigo Filho, Fernando Kok, Laia Turon, Isabel Badell, Iván López Torija, Marta Gomez   +52 more
wiley   +1 more source

Fast Shapley Value Approximation Through Machine Learning With Application in Routing Problems

Networks, EarlyView.
ABSTRACT For many routing applications, it is not only necessary to minimize total costs but also to allocate them to individual customers. In this context, the allocation according to the Shapley value is a well‐known method highly regarded for its fulfillment of major fairness criteria.
Johannes Gückel, Pirmin Fontaine
wiley   +1 more source

Air temperature and particulate matter 2.5 are key environmental drivers of negative air ion dynamics: Results from long-term monitoring in subtropical evergreen broad-leaved forest

Trees, Forests and People
Negative air ions (NAIs) are widely studied for their role in evaluating the therapeutic effects of forests on human health and mitigating air pollution through mechanisms such as neutralizing airborne particulate matter and reducing reactive gaseous ...
Aibo Li, Ziqing Zhao, Yuhao Yang, Kun Sun, Jilai Chen, Benzhi Zhou   +5 more
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