Results 101 to 110 of about 620,051 (323)
From the Hong Kong Anti-Extradition Bill Protests to China’s Wuhan Novel Coronavirus Pneumonia Outbreak: Implications of Two Crises for the Chinese Communist Party’s Governance Model (pp. 1231-1442) [PDF]
Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2020 At the time when Hong Kong’s anti-extradition bill protest movement was entering the transition stage from 2019 to 2020, an earth-shattering event erupted in Mainland China that was soon going to have a far-reaching impact not only on Mainland China, but
Emile Kok-Kheng Yeoh
doaj
End to End Performance Analysis of Relay Cooperative Communication Based on Parked Cars
, 2018 Parking lots (PLs) are usually full with cars. If these cars are formed into a self-organizing vehicular network, they can be new kind of road side units (RSUs) in urban area to provide communication data forwarding between mobile terminals nearby and a ...
Bai, Zhiquan +5 more
core +1 more source
Advanced Science, EarlyView.This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin +18 more
wiley +1 more source
Host susceptibility to severe COVID-19: a retrospective analysis of 487 case outside Wuhan [PDF]
, 2020 Yu Shi +14 more
openalex +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis
Advanced Science, EarlyView.Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan +21 more
wiley +1 more source
Neddylation Facilitates the Antiviral Response in Zebrafish
Frontiers in Immunology, 2019 Neddylation is a type of post-translational protein modifications, in which neural precursor cell expressed developmentally downregulated protein 8 (NEDD8) is covalently conjugated to the lysine residues of target substrates.
Guangqing Yu +21 more
doaj +1 more source
DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut
Advanced Science, EarlyView.Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su +16 more
wiley +1 more source
Zhongguo shuxue zazhiObjective To establish reference intervals for serum soluble transferrin receptor (sTfR) and sTfR/log serum ferritin index (sTfR/lgSF) in apparently healthy adults in the Wuhan area, so as to provide reference for clinical diagnosis and treatment of iron
Cuihua TAO +5 more
doaj +1 more source