Results 81 to 90 of about 5,290,731 (274)

Imaging X-ray spectrometer [PDF]

, 1984
An X-ray spectrometer for providing imaging and energy resolution of an X-ray source is described. This spectrometer is comprised of a thick silicon wafer having an embedded matrix or grid of aluminum completely through the wafer fabricated, for example,
Alcorn, G. E., Grant, P. A., Jackson, J. W., Jr., Marshall, F. E.   +3 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Utilizing Quantum Annealing in Computed Tomography Image Reconstruction

IEEE Transactions on Quantum Engineering
One of the primary difficulties in computed tomography (CT) is reconstructing cross-sectional images from measured projections of a physical object. There exist several classical methods for this task of generating a digital representation of the object,
Kilian Dremel, Dimitri Prjamkov, Markus Firsching, Mareike Weule, Thomas Lang, Anastasia Papadaki, Stefan Kasperl, Martin Blaimer, Theobald O. J. Fuchs   +8 more
doaj   +1 more source

X-rays from Blue Compact Dwarf Galaxies

, 2011
We measured the X-ray fluxes from an optically-selected sample of blue compact dwarf galaxies (BCDs) with metallicities
Calzetti, Dale, Engelbracht, Giacconi, Gil de Paz, Griffith, Hopkins, Hunter, Hunter, Joseph Schmitt, Kaaret, Kennicutt, Kewley, Lee, Lynds, Mark Gorski, Philip Kaaret, Popescu, Relaño, Sargsyan, Schulte-Ladbeck, Telles, Thuan, van Zee, Wu, Wu   +25 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Analysis of the expression of genes involved in proliferation and apoptosis in cervical intraepithelial neoplasias and cancer of the cervix uteri

Опухоли женской репродуктивной системы, 2014
The viral nature of many female genital cancers is now beyond question. By taking into account this fact, the problem of qualitative assessment ofthenatureofcervicalintraepithelialneoplasia(CIN)anditsfocusonprogressiontoinvasivecarcinomabecomesquitenatu ...
V. K. Bozhenko, L. A. Ashrafyan, I. B. Antonova, N. V. Melnikova, O. N. Burmenskaya, D. Yu. Trofimov, E. A. Kudinova, L. Z. Khunova, A. V. Slonov, O. P. Bliznyukov   +9 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

(E)-1-(Benzo[d][1,3]dioxol-5-yl)-3-([2,2′-bithiophen]-5-yl)prop-2-en-1-one: crystal structure, UV–Vis analysis and theoretical studies of a new π-conjugated chalcone

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compound, C18H12O3S2, synthesized by the Claisen–Schmidt condensation method, the essentially planar chalcone unit adopts an s-cis configuration with respect to the carbonyl group within the ethylenic bridge.
Ainizatul Husna Anizaim, Muhamad Fikri Zaini, Muhammad Adlan Laruna, Ibrahim Abdul Razak, Suhana Arshad   +4 more
doaj   +1 more source

X-ray Temperatures, Luminosities, and Masses From XMM-Newton Follow-up of the First Shear-selected Galaxy Cluster Sample

, 2017
We continue the study of the first sample of shear-selected clusters (Wittman et al. 2006) from the initial 8.6 square degrees of the Deep Lens Survey (DLS, Wittman et al.
Deshpande, Amruta J., Hughes, John P., Wittman, David   +2 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source