Results 71 to 80 of about 1,110,244 (228)

Cyclotron lines in X-ray pulsars as a probe of relativistic plasmas in superstrong magnetic fields [PDF]

, 2000
The systematic search for the presence of cyclotron lines in the spectra of accreting X-ray pulsars is being carried on with the BeppoSAX satellite since the beginning of the mission.
Del Sordo, Stefano, Fiume, D. Dal, Frontera, Filippo, Masetti, Nicola, Oosterbroek, Tim, Orlandini, Mauro, Palazzi, Eliana, Parmar, Arvind N., Santangelo, Andrea, Segreto, Alberto   +9 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Bi-LSTM neural network for enhanced radiotherapy: Detection of tissue parameters

Nuclear Engineering and Technology
This study aims to simulate brain tissue and its elements using the MCNPX nuclear code and analyze X-ray emissions for tumor detection. This non-invasive approach offers a promising method for the accurate diagnosis of brain tumors, enabling timely ...
Javad Tayebi, Ali Rezaie, Mohammadreza Rezaie, Mehdi Hassanpour, Mohammad Rashed Iqbal Faruque   +4 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

MODERN APPROACHES IN THE EARLY DETECTION AND DIAGNOSIS OF TUBERCULOSIS OF THE RESPIRATORY SYSTEM

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Background: Timely detection of tuberculosis infection worldwide, at present, remains an urgent problem. Objective: to evaluate the effectiveness of preventive digital X-ray fluorography studies in the timely diagnosis of respiratory tuberculosis ...
Leshchuk T. Yu., Gelberg I. S., Volf S. B.   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Mixed low‐dimensional metal halide perovskite single crystal for low‐detection‐limit x‐ray detection via oriented ion migration

InfoMat
Low‐dimensional metal halide perovskites exhibit exceptional photoelectronic properties and intrinsic stability, positioning them as a promising class of semiconductor materials for light‐emitting devices and photodetectors.
Xuefang Lu, Richeng Lin, Ying Ding, Man Xia, Wei Zheng, Feng Huang   +5 more
doaj   +1 more source

Observation of Galactic Gamma-ray Sources with VERITAS

, 2008
We report on VERITAS observations at energies above 200 GeV of known or potential galactic gamma-ray sources. The observed objects comprise pulsars, pulsar wind nebulae, high-mass X-ray binaries and gamma-ray sources with unknown counterparts in other ...
Felix A. Aharonian, Frank Rieger, G. Maier, null null, Werner Hofmann   +4 more
core   +1 more source