Results 51 to 60 of about 7,474,775 (237)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A Stationary-Sources and Rotating-Detectors Computed Tomography Architecture for Higher Temporal Resolution and Lower Radiation Dose

IEEE Access, 2014
In current computed tomography (CT) architecture, both X-ray tubes and X-ray detectors are rotated mechanically around an object to collect a sufficient number of projections.
Guohua Cao, Baodong Liu, Hao Gong, Hengyong Yu, Ge Wang   +4 more
doaj   +1 more source

Hybrid Imaging Detectors in X-Ray Phase-Contrast Applications

, 2022
X-Ray Phase-Contrast Imaging (XPCI) techniques are gaining increasing interest not only within the synchrotron radiation community, where most of them were first developed and implemented, but also among X-ray imaging experts who make use of standard ...
Brombal, Luca, Rigon, Luigi, Luca Brombal, Luigi Rigon   +3 more
core   +1 more source

In-orbit background for X-ray detectors [PDF]

, 2022
In-orbit background is an unavoidable feature of all space-borne X-ray detectors, and arises both from cosmic sources (diffuse or point-like) and from the interaction of the detectors themselves with the space environment (primary or secondary cosmic ...
Campana, Riccardo
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Detectors and Cultural Heritage: The INFN-CHNet Experience

Applied Sciences, 2021
Detectors are a key feature of the contemporary scientific approach to cultural heritage (CH), both for diagnostics and conservation. INFN-CHNet is the network of the Italian National Institute of Nuclear Physics that develops and applies new ...
Lorenzo Giuntini, Lisa Castelli, Mirko Massi, Mariaelena Fedi, Caroline Czelusniak, Nicla Gelli, Lucia Liccioli, Francesca Giambi, Chiara Ruberto, Anna Mazzinghi, Serena Barone, Francesca Marchegiani, Stefano Nisi, Carmine Lubritto, Simona Altieri, Luca Tortora, Paolo Branchini, Andrea Fabbri, Valerio Graziani, Sergio Barcellos Lins, Laura Guidorzi, Alessandro Lo Giudice, Alessandro Re, Leandro Sottili, Antonella Balerna, Mariangela Cestelli Guidi, Lucilla Pronti, Martina Romani, Fauzia Albertin, Matteo Bettuzzi, Rosa Brancaccio, Maria Pia Morigi, Daniele Alloni, Andrea Salvini, Barbara Smilgys, Michele Prata, Saverio Altieri, Maurizio Bonesini, Daniela Di Martino, Massimiliano Clemenza, Massimo Carpinelli, Piernicola Oliva, Valeria Sipala, Anna Maria Gueli, Stefania Pasquale, Giuseppe Stella, Giancarlo Pepponi, Francesco Grazzi, Francesco Taccetti   +48 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Perspective of perovskite-based X-ray hybrid pixel array detectors

Frontiers in Physics
Compound semiconductors are playing a major role in the production of X-ray pixel detectors for the application in laboratories and beamlines at photon sources.
Michael Fiederle, Michael Fiederle, Tilo Baumbach   +2 more
doaj   +1 more source