Results 231 to 240 of about 5,661,504 (280)

Ultrathin ALD Metal Oxide Coatings Improve the Triboelectric Performance of Regenerated Cellulose. [PDF]

open access: yesNanomaterials (Basel)
Dahlström C   +8 more
europepmc   +1 more source

Effects of diabetes, obesity, and metabolic syndrome on alcohol-associated liver disease: A systematic review. [PDF]

open access: yesHepatol Commun
Peddu DK   +11 more
europepmc   +1 more source

The X-Linked Adrenoleukodystrophy (X-ALD) and Oxidative Stress

open access: yesJournal Of Herbal Pharmacotherapy, 2006
Most of the studies indicate that there is as yet no complete cure for X-ALD. However, methods of the treatment seem to slow rather than treat the disease. One method is the use of Lorenzo's oil in conjunction with a low fat diet, which may help in cerebral X-ALD.
Mohamed A. Al-Omar
openaire   +3 more sources

7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD

Journal of Steroid Biochemistry and Molecular Biology, 2017
X-linked adrenoleukodystrophy (X-ALD) is a genetic disorder induced by a mutation in the ABCD1 gene, which causes the accumulation of very long-chain fatty acids in tissue and plasma. Oxidative stress may be a hallmark of X-ALD. In the plasma of X-ALD patients with different forms of the disease, characterized by high levels of C24:0 and C26:0, we ...
Gérard Lizard, Thomas Nury, Anne Vejux
exaly   +3 more sources

The X-ALD Mouse 2.0

Tijdschrift voor Kindergeneeskunde, 2013
INTRODUCTION X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene that results in elevated very long-chain fatty acids (VLCFA) levels in tissues. X-ALD can manifest as a rapidly progressive and fatal cerebral infl ammatory demyelinating disease (cerebral ALD) or as a slowly progressive noninfl ammatory distal axonopathy (AMN).
Stephan Kemp   +5 more
openaire   +1 more source

X-ALD: centralize care in an international network

Blood, 2011
In this issue of Blood, Miller et al describe the efficacy of hematopoietic cell transplantation (HCT) in 60 patients with childhood cerebral adreno-leucodystrophy (ALD).1 To further improve the outcomes of cellular treatment options in this very rare disease, there is need for coordination of care and a well-functioning international clinical and ...
openaire   +2 more sources

Decreasing serum VLCFA levels in ageing X‐ALD female carriers

Journal of Inherited Metabolic Disease, 2001
AbstractAdrenoleukodystrophy is an X‐linked severe demyelinating disease with pathognomonic accumulation of saturated very long‐chain fatty acids (VLCFA) in tissues and body fluids in affected males. The identification of women heterozygotes is also based on increased serum VLCFA concentrations.
T J, Stradomska, A, Tylki-Szymańska
openaire   +2 more sources

THE GENOTYPE AND PHENOTYPE STUDIES OF 40 CHINESE PATIENTS WITH X-ALD

Neuropediatrics, 2006
Objectives: to studies the genotype and phenotype of 40 Chinese patients with X-ALD. Methods: Clinical features of 40 Chinese patients with X-ALD were studies and mutation spectrums were investigated by polymerase chain reaction (PCR) and sequencing. Results: Among these patients, four were siblings from two kindreds, the others were unrelated.
X Bao   +8 more
openaire   +1 more source

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