Results 111 to 120 of about 6,365,367 (245)

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

open access: yesAdvanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao   +25 more
wiley   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

open access: yesAdvanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan   +13 more
wiley   +1 more source

Blue Light Receptor PHR2‐Mediated Spectrum Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
Blue light suppresses RBSDV through the blue‐light receptor ZmPHR2, which interacts with ZmISP in chloroplasts to trigger ROS burst and antiviral defense. The viral effector P6 enhances ZmPHR2–ZmISP interaction, alters their distribution, and suppresses ROS.
Runyi Chen   +17 more
wiley   +1 more source

X--ray observations of Gamma Ray Burst Afterglows

open access: yes, 2003
The discovery by the BeppoSAX satellite of X-ray afterglow emission from the gamma-ray burst (GRB) which occurred on 28 February 1997 produced a revolution in our knowledge of the gamma-ray burst phenomenon.
FRONTERA, Filippo
core  

TeV gamma-ray emission from accreting binary pulsars [PDF]

open access: yes, 1990
The high-mass X-ray binary SMC X-1 has been observed during the interval 1986-1989 at a threshold γ-ray energy of 0.4 TeV using the University of Durham Mark III air Cerenkov telescope at Narrabri.
Mannings, Vincent, Mannings, V
core  

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

open access: yesAdvanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu   +9 more
wiley   +1 more source

Constraints on the parameters of X-ray burster emission regions

open access: yesThe Astrophysical Journal, 1982
The emission region of an X-ray burster is characterized herein by three quantities: k, the ratio of the emitted flux to the Eddington flux; epsilon-c, the blackbody emissivity; and f, the fraction of the emitting surface which is a distance R from the center of the compact object (a black hole or a neutron star).
openaire   +1 more source

View synthesis for depth from motion 3D x-ray imaging. [PDF]

open access: yes, 2009
The depth from motion or kinetic depth X-ray imaging (KDEX) technique is designed to enhance the luggage screening at airport checkpoints. The technique requires multiple views of the luggage to be obtained from an arrangement of linear X-ray detector ...
Liu, Y
core  

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

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