Results 141 to 150 of about 6,365,367 (245)

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Novel spectral-timing methods for X-ray binary variability studies

, 2012
This work explores the connection between the spectral properties of the X-ray emission produced by black hole X-ray binaries (BHXRBs) and the variability properties of these sources that are embedded in light curves.
Cassatella, Pablo M.
core   +1 more source

Non-destructive ultrasonic testing for identifying concealed weapons and analyzing internal chemical substances. [PDF]

Sci Rep
Lee H, Lim JW, Kwon J, Choi SK, Kim HS, Hwang YI, Kim KB.   +6 more
europepmc   +1 more source

Astrophysical symmetries. [PDF]

Proc Natl Acad Sci U S A, 1996
Trimble V.
europepmc   +1 more source

X-ray bursters and dwarf novae - A correspondence

The Astrophysical Journal, 1977
K. Brecher, P. Morrison, A. Sadun
openaire   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Stochastic analysis of compact stars under composite polytropes. [PDF]

Sci Rep
Nouh MI, El-Essawy SH, Foda MM, Aboueisha MS.   +3 more
europepmc   +1 more source

The X-ray activity of the rapid burster in 1983

The X-ray activity of the rapid burster in 1983
The activity of the rapid burster during 1983, which showed a number of remarkable features is described. At the beginning (August 5-16), only trailing bursts were observed; during August 17-19 similar bursts were observed together with long bursts. The trailing bursts occurred almost periodically with a nearly constant recurring period of 74-90 min ...
openaire   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu, Sheng‐Jie Chang, Xiao‐Wei Liu, Shu‐Bao Zhang, Ying‐Jie Wang, Shan‐Jin Wang   +5 more
wiley   +1 more source