Results 191 to 200 of about 6,365,367 (245)

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat   +7 more
wiley   +1 more source

Single‐Lens Counter‐Focused Ultrashort Laser Pulses for Enhanced Microplasma Formation Inside Silicon

open access: yesLaser &Photonics Reviews, EarlyView.
A polarization‐dependent liquid–crystal spatial light modulator is used to generate coaxial double‐focus laser beams with independently tunable focal separation and intensity. Applied to silicon, this configuration enables counterpropagating pulse interactions using a single focusing element, enhancing nonlinear excitation and achieving near‐critical ...
Niladri Ganguly   +2 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

Electrospun PVA Scaffolds Containing MCM‐41/CNC Nanocomposites for Controlled Drug Release in Wound Dressings

open access: yesPolymer Engineering &Science, EarlyView.
Cellulose nanocrystals extracted from Mauritia flexuosa petiole were combined with MCM‐41 mesoporous silica to create a diclofenac‐loaded hybrid nanocomposite. Incorporation into electrospun PVA scaffolds enabled controlled diclofenac release and high cell viability, highlighting their potential for localized drug delivery.
Karoliny V. Barbosa   +11 more
wiley   +1 more source

Rheological and Mechanical Assessment of Injectable Hydrogels: A Framework for Structure–Property Analysis

open access: yesPolymer Engineering &Science, EarlyView.
A rheological and mechanical assessment framework to construct structure‐property‐application relationships for injectable hydrogels. ABSTRACT Injectable hydrogels have attracted massive research attention thanks to their potential biomedical applications.
Hai Xin   +2 more
wiley   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

open access: yesResponsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang   +6 more
wiley   +1 more source

Biomimetic robots driven by smart materials: Motion forms, stimulation methods and applications

open access: yesResponsive Materials, EarlyView.
Biomimetic robots enhance adaptability by mimicking biological systems, but rigid materials limit performance. Smart materials with stimuli responsiveness and shape adaptability enable more flexible actuation and improved environmental interaction.
Zeyu Yang   +8 more
wiley   +1 more source

Monodisperse Condensed Tannin and Derived Carbon Nanospheres Featuring Well‐Defined Surface‐Structured Metal Species

open access: yesSmall, EarlyView.
Uniform, size‐tunable polyphenol nanospheres are assembled from condensed tannins in water at ambient conditions via controlled supramolecular interactions between tannin and diamines. Their phenolic–amine surfaces template highly dispersed metal species that resist sintering during pyrolysis.
Weitong Wang   +7 more
wiley   +1 more source

PDA‐Engineered 3D‐Printed Polymer–ZrO2 Hybrid Scaffolds Enabling Enhanced Radiopacity, Photothermal Therapy, and Cell Migration Modulation

open access: yesSmall, EarlyView.
A multifunctional 3D‐printed polymer–ZrO2 scaffold is developed to provide intrinsic radiopacity, photothermal responsiveness, and surface bioactivity. Reinforcement with ZrO2 enables real‐time x‐ray visibility and mechanical robustness, while a polydopamine coating facilitates near‐infrared‐triggered drug release and modulates cell migration, thereby ...
Sumin Kang   +10 more
wiley   +1 more source

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