Results 71 to 80 of about 1,110,290 (291)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

YOLOv9 for fracture detection in pediatric wrist trauma X‐ray images

Electronics Letters
The introduction of YOLOv9, the latest version of the you only look once (YOLO) series, has led to its widespread adoption across various scenarios. This paper is the first to apply the YOLOv9 algorithm model to the fracture detection task as computer ...
Chun‐Tse Chien, Rui‐Yang Ju, Kuang‐Yi Chou, Jen‐Shiun Chiang   +3 more
doaj   +1 more source

Symbiotic stars in X-rays II: faint sources detected with XMM-Newton and Chandra [PDF]

, 2014
We report the detection, with ${\it Chandra}$ and XMM-${\it Newton}$, of faint, soft X-ray emission from four symbiotics stars that were not known to be X-ray sources. These four object show a $\beta$-type X-ray spectrum, i.e.
Luna, G. J. M., Mukai, K., Nuñez, N. E., Pillitteri, I.   +3 more
core   +5 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

X-ray Diffraction Tomographic Imaging and Reconstruction [PDF]

, 2011
Material discrimination based on conventional or dual energy X-ray computed tomography (CT) imaging can be ambiguous. X-ray diffraction imaging (XDI) can be used to construct diffraction profiles of objects, providing new molecular signature information ...
Castañón, David, Chen, Ke
core   +1 more source

DETECTING RELATIVISTIC X-RAY JETS IN HIGH-REDSHIFT QUASARS [PDF]

The Astrophysical Journal, 2016
ABSTRACT We analyze Chandra X-ray images of a sample of 11 quasars that are known to contain kiloparsec scale radio jets. The sample consists of five high-redshift (z ≥ 3.6) flat-spectrum radio quasars, and six intermediate redshift (2.1 < z < 2.9) quasars.
Kathryn McKeough, Aneta Siemiginowska, C. C. Cheung, Łukasz Stawarz, Vinay L. Kashyap, Nathan Stein, Vasileios Stampoulis, David A. van Dyk, J. F. C. Wardle, N. P. Lee, D. E. Harris, D. A. Schwartz, Davide Donato, Laura Maraschi, Fabrizio Tavecchio   +14 more
openaire   +6 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

X-ray observations of Be/X-ray binaries in the SMC

, 2003
(shortened) Fifteen Be/X-ray binaries and candidates in the SMC were observed serendipitously with the EPIC instruments of XMM-Newton during two observations of SNR 0047-73.5 and SNR 0103-72.6 in October 2000.
Apparao, Barcons, Buckley, Chakrabarty, Clark, Coe, Coe, Coe, Corbet, Corbet, Corbet, Corbet, Corbet, Corbet, Covino, Dickey, Edge, F. Haberl, Filipovic, Filipovic, Finger, Garmany, Haberl, Haberl, Haberl, Hughes, Hughes, Israel, Israel, Kahabka, Kahabka, Lamb, Lamb, Laycock, Laycock, Liu, Lochner, Macomb, Macomb, Marshall, Meyssonnier, Murphy, Russell, Santangelo, Sasaki, Sasaki, Sasaki, Schmidtke, Southwell, Stevens, Strüder, Turner, W. Pietsch, Wang, Wilson, Yokogawa, Yokogawa   +56 more
core   +1 more source

Cyclotron lines in X-ray pulsars as a probe of relativistic plasmas in superstrong magnetic fields [PDF]

, 2000
The systematic search for the presence of cyclotron lines in the spectra of accreting X-ray pulsars is being carried on with the BeppoSAX satellite since the beginning of the mission.
Del Sordo, Stefano, Fiume, D. Dal, Frontera, Filippo, Masetti, Nicola, Oosterbroek, Tim, Orlandini, Mauro, Palazzi, Eliana, Parmar, Arvind N., Santangelo, Andrea, Segreto, Alberto   +9 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source