Results 41 to 50 of about 1,110,600 (293)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

TfOH-Promoted Reaction of 2,4-Diaryl-1,1,1-Trifluorobut-3-yn-2-oles with Arenes: Synthesis of 1,3-Diaryl-1-CF₃-Indenes and Versatility of the Reaction Mechanisms

Molecules, 2018
The TfOH-mediated reactions of 2,4-diaryl-1,1,1-trifluorobut-3-yn-2-oles (CF3-substituted diaryl propargyl alcohols) with arenes in CH2Cl2 afford 1,3-diaryl-1-CF3-indenes in yields up to 84%. This new process for synthesis of such CF3-indenes is complete
Aleksey V. Zerov, Anna N. Kazakova, Irina A. Boyarskaya, Taras L. Panikorovskii, Vitalii V. Suslonov, Olesya V. Khoroshilova, Aleksander V. Vasilyev   +6 more
doaj   +1 more source

Bunches of misfit dislocations on the onset of relaxation of Si$_{0.4}$Ge$_{0.6}$/Si(001) epitaxial films revealed by high-resolution x-ray diffraction [PDF]

, 2017
The experimental x-ray diffraction patterns of a Si$_{0.4}$Ge$_{0.6}$/Si(001) epitaxial film with a low density of misfit dislocations are modeled by the Monte Carlo method.
Alex Ulyanenkov, Andrei Benediktovitch, Benediktovich A., Bowen D. K., Cressler J. D., Maksym Myronov, Tatjana Ulyanenkova, Vladimir Kaganer   +7 more
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Crystal structure of [4-(2-methoxyphenyl)-3-methyl-1-phenyl-6-trifluoromethyl-1H-pyrazolo[3,4-b]pyridin-5-yl](thiophen-2-yl)methanone

Acta Crystallographica Section E, 2014
The title compound, C26H18F3N3O2S, a 2-methoxy-substituted derivative, is closely related to its 4-methyl- and 4-chloro-substituted analogues and yet displays no structural relationships with them.
V. Rajni Swamy, P. Gunasekaran, R. V. Krishnakumar, N. Srinivasan, P. Müller   +4 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

X-Ray Diffraction

, 2016
Abstract This chapter analyzes the diffraction of X-rays from crystals. The wavelengths of X-rays can be of the same order as the interatomic spacings in crystals. In optics we are familiar with the fact that a collection of equally spaced lines (a line grating) scatters (or diffracts) light at discrete angles relative to an incoming ...
  +4 more sources

X- ray diffraction and dielectric properties of PbSe thin films

Iraqi Journal of Physics, 2019
Lead selenide PbSe thin films of different thicknesses (300, 500, and 700 nm) were deposited under vacuum using thermal evaporation method on glass substrates.
Bushra A. Hasan
doaj   +1 more source

Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy

Photonics, 2022
X-ray diffraction microscopy (XDM) is an established lens-less imaging method extensively practiced at synchrotrons and X-ray free-electron lasers (XFELs). XDM is broadly operated in two different modes: scanning and non-scanning.
Katarzyna Kunio, Shirly Espinoza, Krishna P. Khakurel   +2 more
doaj   +1 more source

Modelling a Transition-Edge Sensor X-ray Microcalorimeter Linear Array for Compton Profile Measurements and Energy Dispersive Diffraction

, 2019
Transition-edge sensors are a type of superconducting detector that offers high energy resolution based on their sharp resistance-temperature feature in the superconducting-to-normal transition.
Gades, Lisa M., Guruswamy, Tejas, Miceli, Antonino, Patel, Umeshkumar M., Quaranta, Orlando, Yan, Daikang   +5 more
core   +1 more source